Uranium monosulfide (US) is an inorganic chemical compound of uranium and sulfur. It is produced by combining uranium metal powder with hydrogen sulfide to form uranium disulfide, followed by sulfur loss during high-temperature, vacuum annealing.

Magnetically, the compound is paramagnetic at room temperature, with a Curie Temperature of 180 K. It has the largest known magnetocrystalline anisotropy of any cubic system.