Vasudeva II (Middle Brahmi script: Bā-zo-de-o Sanskritzied to "Vasudeva") was a Kushan emperor who ruled c. 275–300. He was probably the successor of Kanishka III and may have been succeeded by an emperor named Shaka Kushan.

Vasudeva II probably only was a local ruler in the area of Taxila, in western Punjab, under the suzerainty of the Gupta Empire.

Vasudeva II was a contemporary of Hormizd I Kushanshah of the Kushano-Sasanians, as he is known to have overstruck a large quantity of the early copper coins of Hormizd I issued south of the Hindu-Kush.