Warthen is an unincorporated community and census-designated place (CDP) in Washington County, Georgia, United States. The community is located at the junction of State Routes 15 and 102, 8.3 miles (13.4 km) north of Sandersville. Warthen has a post office with ZIP code 31094.

The 2020 census listed a population of 132.

Warthen was the first settlement erected in Washington County and was founded to be the site of the superior courts and the jail for the county. Warthen was erected as a settlement in 1754. It is located in a coastal plain and once embraced territory from the Cherokee corner.

Warthen was an early holder of the Washington County county seat until the seat was transferred to Sandersville in 1796.

The Georgia General Assembly incorporated Warthen in 1812. Eventually, the community lost its charter and today it occupies an unincorporated area.

Warthen has been declared a historic site, and inscribed on the National Register of Historic Places as the Warthen Historic District.

The town of Warthen is home to the oldest hewn log jail in Georgia. This jail was once the confinement space of Aaron Burr in 1804 on his journey to Richmond, Virginia for trial concerning his charges of treason against Alexander Hamilton.

Warthen, Georgia is historically known for being part of Washington County's cotton crops. The industry of cotton brought settlers to the area and farmers raised a variety of crops. After the invention of the cotton gin, cotton became a major crop in the county.