Zhumadian (simplified Chinese: 驻马店; traditional Chinese: 駐馬店; pinyin: Zhùmǎdiàn; postal: Chumatien) is a prefecture-level city in southern Henan province, China. It borders Xinyang to the south, Nanyang to the west, Pingdingshan to the northwest, Luohe to the north, Zhoukou to the northeast, and the province of Anhui to the east.

As of the 2020 Chinese census, its total population was 7,008,427 inhabitants whom 1,466,913 lived in the built-up (or metro) area made of Yicheng District and Suiping County now conurbated.

It was once the center of the Cai state during the Eastern Zhou era. The state leaves its name in several of the subdivisions including Shangcai County and Xincai County.

The prefecture-level city of Zhumadian administers 1 district and 9 counties.

Zhumadian is situated at 32° 18'−33° 35' N latitude, and 113° 10'−115° 12' E longitude, with a maximum east–west width of 191.5 kilometres (119.0 mi), and at most 137.5 kilometres (85.4 mi) long from south to north. The area of the prefecture is 15,083 square kilometres (5,824 sq mi), occupying 8.9% of the total provincial area. Neighbouring prefectures are:

The terrain is dominated by mountains, hills, hillocks, and plains.

Zhumadian has a four-season, monsoon-influenced humid subtropical climate (Köppen Cwa), with cold, somewhat damp, winters, and hot, humid summers. The monthly 24-hour average temperature ranges from 1.5 °C (34.7 °F) in January to 27.3 °C (81.1 °F) in July, while the annual mean is 15.15 °C (59.3 °F). More than 60% of the annual precipitation of 990 mm (39 in) occurs from June to September. With monthly percent possible sunshine ranging from 39% in March to 46% in four months, the city receives 1,927 hours of bright sunshine annually.

Mainly wheat, maize, peanut, sesame, green beans and tobacco are grown.