10 News is the national news and current affairs division of Network 10. Its flagship program airs at 5:00 pm on weekday evenings, with editions produced from studios in Sydney, Melbourne, Brisbane, Adelaide and Perth. National bulletins are presented from the network's main studios in Pyrmont, Sydney.

The news division also draws upon the resources of CBS News, and among non-Paramount Skydance sources, ITN, APTN and Reuters for select international coverage.

Network 10's news service was introduced on 2 August 1964 with the launch of ATV-10 in Melbourne, followed on 5 April 1965 by TEN-10 in Sydney.

The network was the first to introduce dual-anchored hour-long news bulletins in the form of Eyewitness News from 1973 onwards. The 1980s were the network's most successful period as a news provider with its local Sydney, Melbourne and Brisbane bulletins often rating highest for their 6pm timeslots. Network 10's flagship national nightly bulletin news services has undergone a number of name changes since inception in 1965 including: Ten News, Ten Evening News, and Ten Eyewitness News, whilst state bulletins titles have included ATV News in Melbourne, SASNEWS in Adelaide and Newswatch in Brisbane.

A major change to the service occurred on 20 January 1992 when all five of its local bulletins were moved to the 5pm time slot. In 1994, all local weekend bulletins were axed across the network and replaced by a 30-minute network bulletin from Sydney – Ten Weekend News, initially presented by John Gatfield and later by Tracey Spicer, Natarsha Belling and Bill Woods.

10 News has often been described as a 'training ground' for some of Australia's best-known television journalists. Some of the best-known reporters and presenters who launched or spent a major part of their careers at Network 10 include Jana Wendt, Kerry O'Brien, Katrina Lee, Charles Slade, Ann Sanders, Steve Liebmann, Tim Webster, Ron Wilson, Anne Fulwood, Juanita Phillips, Harry Potter, Liz Hayes, Jo Pearson, David Johnson, Bill McDonald, Chris Masters, Larry Emdur, Eddie McGuire, John Gatfield, Kay McGrath, Graeme Goodings, Sharyn Ghidella, Laurie Oakes, Geraldine Doogue, Helen Kapalos, Jennifer Keyte, Deborah Knight, Bruce McAvaney, Nathan Templeton, Mel McLaughlin, Karl Stefanovic, Mark Beretta, Amber Sherlock and George Donikian amongst others.

In September 2010, the network announced a major expansion of its news service. From 24 January 2011, It expanded its evening news output by introducing a national current affairs program at 6pm, 6PM with George Negus (later 6.30 with George Negus), and an additional local bulletin at 6:30pm on weeknights, under the Ten Evening News brand. In addition, the network announced the re-introduction of local weekend bulletins at 6pm and the axing of its 5pm national bulletin.

Two months after the relaunch, the national weekend bulletins were re-introduced owing to poor ratings, although the 6pm local bulletins continued to air. Later that month, the network dropped its 6:30pm local bulletins on weeknights, extended Ten News at Five to 90 minutes and moved George Negus' program to 6:30pm each weeknight. The changes were introduced on Monday 4 April 2011.