In 6-dimensional geometry, the 1₂₂ polytope is a uniform polytope, constructed from the E₆ group. It was first published in E. L. Elte's 1912 listing of semiregular polytopes, named as V₇₂ (for its 72 vertices).

Its Coxeter symbol is 1₂₂, describing its bifurcating Coxeter-Dynkin diagram, with a single ring on the end of the 1-node sequence. There are two rectifications of the 1₂₂, constructed by positions points on the elements of 1₂₂. The rectified 1₂₂ is constructed by points at the mid-edges of the 1₂₂. The birectified 1₂₂ is constructed by points at the triangle face centers of the 1₂₂.

These polytopes are from a family of 39 convex uniform polytopes in 6-dimensions, made of uniform polytope facets and vertex figures, defined by all permutations of rings in this Coxeter-Dynkin diagram: .

The 1₂₂ polytope contains 72 vertices, and 54 5-demicubic facets. It has a birectified 5-simplex vertex figure. Its 72 vertices represent the root vectors of the simple Lie group E₆.

It is created by a Wythoff construction upon a set of 6 hyperplane mirrors in 6-dimensional space.

The facet information can be extracted from its Coxeter-Dynkin diagram, .

Removing the node on either of 2-length branches leaves the 5-demicube, 1₂₁, .

The vertex figure is determined by removing the ringed node and ringing the neighboring node. This makes the birectified 5-simplex, 0₂₂, .