The 2003 UEFA Champions League final was a football match that took place at Old Trafford in Manchester, England on 28 May 2003 to decide the winner of the 2002–03 UEFA Champions League. The match was contested by two Italian teams: Juventus and Milan. The match made history as it was the first time two clubs from Italy had faced each other in the final. It was also the second intra-national final of the competition, following the all-Spanish 2000 UEFA Champions League final between Real Madrid and Valencia three years earlier. Milan won the match via a penalty shoot-out after the game had finished 0–0 after extra time. It gave Milan their sixth success in the European Cup.

Juventus entered the 2002–03 UEFA Champions League as 2001–02 Serie A champions and so qualified for the group phase, Milan finished fourth so started off in the third qualifying round.

Juventus went into the Champions League final as champions of Italy for the 27th time. Milan came third in the league, finishing with eleven fewer points than Juventus, but would win the 2002–03 Coppa Italia. The league games between the two teams in 2002–03 had each side winning their home fixture 2–1.

Old Trafford, the home of Manchester United, was selected to host the match in December 2001, following a meeting of the UEFA Executive Committee in Nyon, Switzerland, at the same time as Estadio de La Cartuja in Seville was selected to host the 2003 UEFA Cup Final. It was selected ahead of the likes of the Millenium Stadium in Cardiff, the Santiago Bernabeu Stadium in Madrid, the Stade de France in Saint-Denis near Paris, and the Amsterdam Arena.

It would be the first time the stadium had hosted a major European final, although it had been the venue for both the two-legged 1968 Intercontinental Cup between Manchester United and Argentine club Estudiantes de La Plata, and the 1991 European Super Cup between Manchester United and Yugoslavian club Red Star Belgrade, which had been scheduled to be played over two legs, only for the Yugoslavian leg to be cancelled due to the wars in the country at the time.

The stadium had recently undergone a major expansion; following the mandatory conversion to an all-seater venue as a result of the Taylor Report and ahead of England hosting UEFA Euro 1996, the stadium's North Stand was expanded to three tiers, with a capacity of 25,500 spectators. This was followed by the addition of second tiers to the East and West Stands, which brought the overall capacity of the stadium to 68,217.

As has taken place for every Champions League final since 1997, a ceremonial handover of the European Champion Clubs' Cup from the holders to the host city took place on 3 April 2003. After receiving the trophy from a representative of holders Real Madrid in the ceremony at the Manchester Town Hall, UEFA Chief Executive Gerhard Aigner presented it to the Lord Mayor of Manchester, Roy Walters. Former Real Madrid players Alfredo Di Stéfano, Francisco Gento, Amancio and Emilio Butragueño, as were Manchester United manager Alex Ferguson, members of the club's 1968 European Cup final team, and members of Liverpool and Manchester City's past European trophy-winning teams.

Also in April 2003, a 24-hour football match – named the "Starball Match" in reference to the logo of the UEFA Champions League – was played in Manchester's Albert Square. It was the second Starball Match, after the inaugural match was held in Glasgow ahead of the 2002 UEFA Champions League final at Hampden Park. Over 1,000 players participated in the match, playing for sides named "Internazionale Manchester" and "Real Mancunian", in reference to Italian club Inter Milan and Spanish club Real Madrid. Internazionale Manchester won the match 252–162.