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3-Hydroxykynurenine
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| Names | |
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| IUPAC name
2-Amino-4-(2-amino-3-hydroxyphenyl)-4-oxobutanoic acid
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| Identifiers | |
3D model (JSmol)
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| KEGG | |
| MeSH | 3-hydroxykynurenine |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C10H12N2O4 | |
| Molar mass | 224.21 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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3-Hydroxykynurenine is a metabolite of tryptophan, which filters UV light in the human lens.[1] It is one of two pigments identified as responsible for the goldenrod crab spider's (Misumena vatia) yellow coloration.
References
[edit]- ^ Malina, HZ; Martin, XD (1995). "Deamination of 3-hydroxykynurenine in bovine lenses: a possible mechanism of cataract formation in general". Graefes Arch Clin Exp Ophthalmol. 233 (1): 38–44. doi:10.1007/bf00177784. PMID 7721122. S2CID 25414197.
- ^ Schwarcz, Robert; John P. Bruno; Paul J. Muchowski; Hui-Qiu Wu (July 2012). "Kynurenines in the Mammalian Brain: When Physiology Meets Pathology". Nature Reviews Neuroscience. 13 (7): 465–477. doi:10.1038/nrn3257. PMC 3681811. PMID 22678511.