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5-HO-DiPT

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5-HO-DiPT

5-HO-DiPT, also known as 5-hydroxy-N,N-di-iso-propyltryptamine, is a tryptamine derivative which acts as a serotonin receptor agonist. It is primarily known as a metabolite of the better known psychoactive drug 5-MeO-DiPT, but 5-HO-DiPT has also rarely been encountered as a designer drug in its own right. Tests in vitro show 5-HO-DiPT to have high serotonin 5-HT2A receptor affinity and good selectivity over the serotonin 5-HT1A receptor, while being more lipophilic than the related drug bufotenine (5-HO-DMT), which produces primarily peripheral effects.

Analogues of 5-HO-DiPT include diisopropyltryptamine (DiPT), 4-HO-DiPT (iprocin), 4-AcO-DiPT (ipracetin), 5-MeO-DiPT, bufotenin (5-HO-DMT), 5-AcO-DMT, 5-HO-DET, 5-HO-DPT, and α-methylserotonin (5-HO-AMT), among others.

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