The Andhra Pradesh State Road Transport Corporation (abbreviated as APSRTC) is the state-owned road transport corporation in the Indian state of Andhra Pradesh. Its headquarters is located at NTR Administrative Block of RTC House in Pandit Nehru bus station of Vijayawada. Many other Indian metros and towns in Telangana, Tamil Nadu, Karnataka, Odisha and Chhattisgarh are also linked with the APSRTC services. It was merged into the state government after the creation of AP Public Transport Department (APPTD) in September 2019.

In the erstwhile Hyderabad State, bus services were initially started in June 1932 as part of the Nizam State Rail and Road Transport Department, a wing of Nizam State Railway. APSRTC was formed on 11 January 1958 as per "Road Transport Corporations Act 1950". Consequent upon bifurcation of Andhra Pradesh state into Telangana and residual Andhra Pradesh, Telangana State Road Transport Corporation is operated as a separate entity from 3 June 2015. APSRTC is working from Vijayawada (Pandit Nehru Bus Stand) as Headquarters for the state of Andhra Pradesh. APSRTC has a target to convert its entire bus fleet to electric buses using both battery electric buses and fuel cell buses by the year 2029.

The organisation is divided into four zones with twelve regional managers. As of March 2025, it has a total of 11,495 buses (government-owned 8716; hire on rental 2779) operating in 38.59 lakh kilometers and has a total of 423 bus stations and 129 bus depots. The APSRTC connects 14,123 villages, transports 35.09 lakh passengers, and makes 14.46 crore rupees in earnings per day. On average, each bus covers 336 kilometers and makes 12,580 rupees in earnings per day. From 30 January 2019, all the APSRTC vehicles in the state are registered as AP–39, followed by "Z" and four digits.

The organisation has a total of 46,051 employees and several trade unions representing them. The "Andhra Pradesh Public Transport Department Employees Union" or "APPTD Employees Union" was originally formed in July 1952 as "APSRTC Employees Union" and is affiliated with the All India Trade Union Congress and AP JAC Amaravati. The APSRTC Staff and Workers Federation was established in 2008 and is affiliated with the Centre of Indian Trade Unions. The APSRTC National Mazdoor Union, APSRTC Karmika Parishat (affiliated to Telugu Desam Party) and YSR RTC Mazdoor Union (affiliated to YSR Congress Party) also represent sections of the employees.

The Andhra Pradesh State Road Transport Corporation operates various services both for urban transport as well as intercity and village transport, and cargo services.

Various bus services operated by the Andhra Pradesh State Road Transport Corporation.

These services offered by APSRTC to carry parcels, couriers, goods and bulk materials. These services can be booked and utilised by public for shifting their goods and valuables. Every bus depot in APSRTC having one DGT Bus.

As of March 2019^[update], the organisation had gross earnings of ₹5,995 crores, and with an accumulated loss of ₹6,445 crores.