Amy Hennig was born in the United States. Details about her exact birthplace and early childhood are relatively scarce, as Hennig is a private individual.

Hennig attended the University of California, Berkeley, where she studied English Literature. This background would later prove invaluable in her storytelling roles within the video game industry.

While not definitively confirmed, some sources suggest Hennig initially had aspirations for a career in film, aligning with her interest in storytelling and visual mediums.