Atlas is a family of US missiles and space launch vehicles that originated with the SM-65 Atlas. The Atlas intercontinental ballistic missile (ICBM) program was initiated in the late 1950s by General Dynamics through its Convair division. Atlas was a liquid propellant rocket burning RP-1 kerosene fuel with liquid oxygen in three engines configured in an unusual "stage-and-a-half" or "parallel staging" design: two outboard booster engines were jettisoned along with supporting structures during ascent, while the center sustainer engine, propellant tanks and other structural elements remained connected through propellant depletion and engine shutdown.

The Atlas name was originally proposed by Karel Bossart and his design team working at Convair on project MX-1593. Using the name of a mighty Titan from Greek mythology reflected the missile's place as the biggest and most powerful at the time. It also reflected the parent company of Convair, the Atlas Corporation.

The missiles saw only brief ICBM service, and the last squadron was taken off operational alert in 1965. However, from 1962 to 1963 Atlas boosters launched the first four US astronauts to orbit the Earth (in contrast to the preceding two Redstone suborbital launches). The Atlas-Agena and Atlas-Centaur satellite launch vehicles were also derived directly from the original Atlas. The Atlas-Centaur was evolved into the Atlas II, various models of which were launched 63 times between 1991 and 2004. There were only six launches of the succeeding Atlas III, all between 2000 and 2005. The Atlas V is still in service, with launches planned into the mid-2020s.

More than 300 Atlas launches have been conducted from Cape Canaveral Space Force Station in Florida and 285 from Vandenberg Space Force Base in California.

The Atlas was used as an expendable launch system, with both the Agena and Centaur upper stages, for the Mariner space probes used to explore Mercury, Venus, and Mars (1962–1973); and to launch ten of the Mercury program missions (1962–1963).^{[citation needed]}

The first successful test launch of an SM-65 Atlas missile was on 17 December 1957. Approximately 350 Atlas missiles were built.

The Atlas boosters would collapse under their own weight if not kept pressurized with nitrogen gas in the tanks when devoid of propellants. The Atlas booster was unusual in its use of "balloon" tanks. The rockets were made from very thin stainless steel that offered minimal or no rigid support. It was pressure in the tanks that gave the rigidity required for space flight. In order to save weight they were not painted and needed a specially designed oil to prevent rust. This was the original use of WD-40 water displacement oil.

The SM-65 Atlas was used as a first stage for satellite launch vehicles for half a century. Many were eventually converted to orbital launch vehicles after they were removed from service as missiles. Missiles converted into Atlas E/F "space boosters" were used to launch the early "Block I" GPS satellites.