William James Murray (born September 21, 1950) is an American actor and comedian, known for his deadpan delivery in roles ranging from studio comedies to independent dramas. He has received several accolades including a BAFTA Award, a Golden Globe Award, and two Primetime Emmy Awards as well as a nomination for an Academy Award. Murray was awarded the Mark Twain Prize for American Humor in 2016.

Murray became a national presence on Saturday Night Live from 1977 to 1980, receiving a Primetime Emmy Award for Outstanding Writing for a Variety Series. He established his stardom by acting in a string of successful comedy films, including Meatballs (1979), Caddyshack (1980), Stripes (1981), Scrooged (1988), What About Bob? (1991), and Groundhog Day (1993). He also had supporting roles in Tootsie (1982), Little Shop of Horrors (1986), Ed Wood (1994), Kingpin (1996) and Osmosis Jones (2001). Murray also starred as Dr. Peter Venkman in Ghostbusters (1984), and Ghostbusters II (1989) and has reprised his role in various projects within the Ghostbusters franchise. He has done voice acting work in films, such as Garfield (2004), Garfield: A Tail of Two Kitties (2006), Fantastic Mr. Fox (2009), The Jungle Book (2016) and Isle of Dogs (2018).

He has frequently collaborated with director Wes Anderson, acting in ten of his films starting with Rushmore (1998), followed by roles in films such as The Royal Tenenbaums (2001), The Life Aquatic with Steve Zissou (2004), Fantastic Mr. Fox (2009), Moonrise Kingdom (2012), The Grand Budapest Hotel (2014), and Isle of Dogs (2018). He played an aging actor in Sofia Coppola's dramedy Lost in Translation (2003), earning Golden Globe and BAFTA Awards as well as a nomination for the Academy Award for Best Actor. He also acted in films such as Broken Flowers (2005), Zombieland (2009), Get Low (2010), Hyde Park on Hudson (2012), St. Vincent (2014), On the Rocks (2020), and The Friend (2024).

Murray was born on September 21, 1950, in Evanston, Illinois, to Lucille, a mail room clerk, and Edward J. Murray, a lumber salesman. He attended Loyola Academy, an all-boys Jesuit school in Wilmette, Illinois, a northern suburb of Chicago.

Murray and his eight siblings grew up in an Irish Catholic family. His paternal grandfather was from County Cork, while his maternal ancestors were from County Galway. Three of his siblings, John Murray, Joel Murray and Brian Doyle-Murray, are also actors. A sister, Nancy, is an Adrian Dominican nun in Michigan; she has traveled the United States in two one-woman programs, portraying Catherine of Siena and Dorothy Stang. His brother Ed Murray died in 2020. Their father died in 1967 at the age of 46 from complications of diabetes when Bill was 17.

As a youth, Murray read children's biographies of American heroes like Kit Carson, Wild Bill Hickok and Davy Crockett. He attended St. Joseph's grade school and Loyola Academy. During his teen years, he worked as a golf caddy to fund his education at the Jesuit high school, was the lead singer of a rock band (the Dutch Masters) and took part in high school and community theater. One of his sisters had polio and his mother suffered several miscarriages.

After graduating from Loyola Academy, Murray attended Regis University in Denver, Colorado, taking pre-medical courses, but quickly dropped out and returned to Illinois. In 2007, Regis awarded him an honorary Doctor of Humanities degree. On September 21, 1970, his 20th birthday, the police arrested Murray at Chicago's O'Hare Airport for trying to smuggle 10 lb (4.5 kg) of cannabis, which he had allegedly intended to sell. It was discovered after Murray joked to the passenger next to him that he had packed a bomb in his luggage. Murray was convicted and sentenced to probation.

With an invitation from his older brother Brian, Murray got his start at Chicago's The Second City, an improvisational comedy troupe, studying under Del Close. In 1974, he moved to New York City and was recruited by John Belushi as a featured player on The National Lampoon Radio Hour.