Biopolitics is a concept popularized by the French philosopher Michel Foucault in the mid-20th century. At its core, biopolitics explores how governmental power operates through the management and regulation of a population's bodies and lives.

This interdisciplinary field scrutinizes the mechanisms through which political authorities and institutions exercise control over populations which goes beyond conventional forms of governance. This encompasses areas such as the regulation of health, reproduction, sexuality, and other aspects of biological existence. The governmental power of biopolitics is exerted through practices such as surveillance, healthcare policies, population control measures, gender-based laws, and the implementation of biometric identification systems.

Foucault's thesis claims that contemporary power structures are increasingly preoccupied with the administration of life itself, rather than solely focusing on individual behaviors or actions. Accordingly, biopolitics entails the governance of populations as biological entities, with an emphasis on optimizing their health, productivity, and reproductive capacities in manners conducive to broader political and economic objectives. In its essence, biopolitics investigates how political power intersects with biological life, shaping the bodies, behaviors, and well-being of populations through diverse strategies and controls.

Previous notions of the concept can be traced back to the Middle Ages in John of Salisbury's work Policraticus, in which the term body politic was coined and used. The term biopolitics was first used by Rudolf Kjellén, a political scientist who also coined the term geopolitics, in his 1905 two-volume work The Great Powers. Kjellén used the term in the context of his aim to study "the civil war between social groups" (comprising the state) from a biological perspective, and thus named his putative discipline "biopolitics". In Kjellén's organicist view, the state was a quasi-biological organism, a "super-individual creature". The Nazis also subsequently used the term in the context of their racial policy, with Hans Reiter using it in a 1934 speech to refer to their concept of nation and state based on racial supremacy.

In contemporary US political science studies, usage of the term is mostly divided between a poststructuralist group using the meaning assigned by Foucault (denoting social and political power over life) and another group that uses it to denote studies relating biology and political science. In the work of Foucault, biopolitics refers to the style of government that regulates populations through "biopower" (the application and impact of political power on all aspects of human life).

Morley Roberts, in his 1938 book Bio-politics argued that a correct model for world politics is "a loose association of cell and protozoa colonies". Robert E. Kuttner used the term to refer to his particular brand of "scientific racism", as he called it, which he worked out with noted antisemite Eustace Mullins, with whom Kuttner co-founded the Institute for Biopolitics in the late 1950s, and also with Glayde Whitney, a behavioral geneticist. Most of his opponents label his model as antisemitic. Kuttner and Mullins were inspired by Morley Roberts, who was in turn inspired by Arthur Keith, or both were inspired by each other and either co-wrote together (or with the Institute of Biopolitics) Biopolitics of Organic Materialism dedicated to Roberts and reprinted some of his works.

In the work of Michael Hardt and Antonio Negri, biopolitics is framed in terms of anti-capitalist insurrection using life and the body as weapons; examples include flight from power and, "in its most tragic and revolting form", suicide terrorism, conceptualized as the opposite of biopower, which is seen as the practice of sovereignty in biopolitical conditions.

According to Professor Agni Vlavianos Arvanitis, biopolitics is a conceptual and operative framework for societal development, promoting bios (Greek for "life") as the central theme in every human endeavor, be it policy, education, art, government, science or technology. This concept uses bios as a term referring to all forms of life on our planet, including their genetic and geographic variation.