Cancale (French pronunciation: [kɑ̃kal]; Breton: Kankaven; Gallo: Cauncall) is a commune in the Ille-et-Vilaine department in Brittany in northwestern France. It is known as the birthplace of Saint Jeanne Jugan.

Inhabitants of Cancale are called Cancalais in French.

Cancale is located at the western end of the bay of Mont-Saint-Michel, on the coasts of Ille-et-Vilaine (Côte d'Émeraude), fifteen kilometers east of Saint-Malo. The bay of Cancale is delimited by the pointe des Roches Noires in the south and the pointe des Crolles in the north.

Cancale lies along the coast to the east of Saint-Malo. It is a picturesque fishing port popular with visitors, many of whom are drawn by its reputation as the "oyster capital" of Brittany. Though a small town, it is well served by a large number of restaurants, many specialising in seafood. When not eating one can sit and watch the bustle of this busy little town with many stalls selling crustaceans of all types.

The oyster market (marché aux huîtres) at the harbour at the end of Quai de l'Administrateur en Chef Thomas offers a wide variety of local oysters at producer prices. At low tide part of the vast oyster beds can visited.

There is a pleasant coastal path which permits a circular walk from the town to the Pointe du Grouin with views across the bay towards Mont Saint-Michel.

Eugène Feyen painted Cancale and the inhabitants with the oyster-picking Cancalaises for several decades around 1865–1908. Vincent van Gogh wrote that "Eugène Feyen is one of the few painters who pictures intimate modern life as it is really, and does not turn it into fashion plates".

John Singer Sargent featured Cancale in his works: Fishing for Oysters at Cancale and Low tide at Cancal Harbour Archived 1 April 2023 at the Wayback Machine