Christos Patsatzoglou (Greek: Χρήστος Πατσατζόγλου; born 19 March 1979) is a Greek former professional footballer who played as a right-back or defensive midfielder.

Patsatzoglou started his career in Skoda Xanthi before being transferred to Olympiacos where he won several national titles. He then moved to Omonia in Cyprus where he won the double. Patsatzoglou also had spells with AEK Athens and PAS Giannina. Patsatzoglou was capped on 45 occasions with Greece.

Born and raised in Athens to a Romani family of the Greek Orthodox faith, Christos started playing football for his hometown's local youth team Agia Eleousa and earned a place in the squad of Greece U17. His talent was spotted by Skoda Xanthi's scouts and he was transferred to the club in 1996. He played for their first team for four years, from 1996–1997 to 1999–2000 where he won the Best Young Player award in his final season in Xanthi in 1999–2000.

Alongside Giourkas Seitaridis, Christos was considered to be one of Greece's footballing talents and was pursued to be signed by the country's "Big 3"; Olympiacos, AEK Athens and Panathinaikos, though he chose to sign with Olympiacos Piraeus. He was a consistent performer until he was injured in 2003, at a derby game between Olympiacos and AEK Athens. Just before he suffered the injury, Christos was in the form of his life while playing for Olympiacos and Greece, as he was an athletic and solid defender at the back and skillful going forward and was considered to be one of the top defenders of European football through his performances for Olympiacos while playing in the UEFA Champions League and UEFA Cup anda good defender in all of Greece through his performances for Olympiacos in the Alpha Ethniki and Greek Football Cup .

He was being courted by Manchester United who Olympiacos declined a £6 million offer from them as Patsatzoglou after being watched by a scout who was sent to Greece from Old Trafford for a long time to watch his games was in Alex Ferguson's plans to rebuild his defensive lines but Olympiacos were not willing at all to give up their club's and country's star defender as he was so crucial to the success of Olympiacos and one of the pin-up boys of Greek football from the early 2000s and he remained at the Greek giants where down the track he copped a bad injury which kept him sidelined for a long while. He worked to recover from his injury for about two years, and made his comeback near the end of the 2004–05 season.

He stated that he was healthy again and that it was up to his coach, Trond Sollied to play him now. Sollied was not sure if Patsatzoglou could play again in such a competitive level, but he was willing to give him more chances in the 2005–06 season.

During the 2006–07 season, Patsatzoglou suffered another knee injury, unrelated to his previous one, at the away Champions League match against Roma. Upon his return, he played a handful of games.

In the 2007–08 season, Patsatzoglou scored the winning the goal in the UEFA Champions League match against Werder Bremen. The goal would lead to Olympiacos' first Champions League away win, finishing 1–3.