Born to Corey and Candi Gauff, who have been instrumental in her career. Her parents' athletic backgrounds shaped her early life and provided significant support for her tennis aspirations. She has two younger brothers, Codey and Cameron.

Gauff was homeschooled to accommodate her tennis training and travel schedule. Despite her demanding career, she has expressed interest in pursuing higher education and has mentioned subjects like history and science as potential areas of study. She also enjoys spending time with friends, listening to music, and fashion.

Gauff maintains a close relationship with her family, who are frequently seen supporting her at tournaments. Her parents' guidance and encouragement have been crucial to her success. Her family provides a sense of normalcy and stability amid the pressures of her career.

Coco has developed friendships with other players on the WTA tour, including Jessica Pegula and Caty McNally. She also received mentorship and guidance from Serena Williams, whom she idolizes. These relationships provide a sense of community and support within the competitive world of professional tennis.

As of late 2023, Coco Gauff keeps her romantic life private. While there's public speculation, there is no confirmed information available about her romantic relationships. She prefers to focus on her career and personal growth.