Command guidance is a type of missile guidance in which a ground station or aircraft relay signals to a guided missile via radio control or through a wire connecting the missile to the launcher and tell the missile where to steer to intercept its target. This control may also command the missile to detonate, even if the missile has a fuze.

Typically, the system giving the guidance commands is tracking both the target and the missile or missiles via radar. It determines the positions and velocities of a target and a missile, and calculates whether their paths will intersect. If not, the guidance system will relay commands to a missile, telling it to move the fins in a way that steers in the direction needed to maneuver to an intercept course with the target. If the target maneuvers, the guidance system can sense this and update the missiles' course continuously to counteract such maneuvering. If the missile passes close to the target, either its own proximity or contact fuze will detonate the warhead, or the guidance system can estimate when the missile will pass near a target and send a detonation signal.

On some systems there is a dedicated radio antenna or antennas to communicate with a missile. On others, the radar can send coded pulses which a missile can sense and interpret as guidance commands. Sometimes to aid the tracking station, a missile will contain a radio transmitter, making it easier to track. Also, sometimes a tracking station has two or more radar antennas: one dedicated to track a missile and one or more dedicated to track targets. These types of systems are most likely to be able to communicate with a missile via the same radar energy used to track it.

The CLOS system uses only the angular coordinates between the missile and the target to ensure the collision. The missile is made to be in the line of sight between the launcher and the target (LOS), and any deviation of the missile from this line is corrected. Since so many types of missile use this guidance system, they are usually subdivided into four groups: A particular type of command guidance and navigation where the missile is always commanded to lie on the line of sight (LOS) between the tracking unit and the aircraft is known as command to line of sight (CLOS) or three-point guidance. That is, the missile is controlled to stay as close as possible on the LOS to the target. More specifically, if the beam acceleration is taken into account and added to the nominal acceleration generated by the beam-rider equations, then CLOS guidance results. Thus, the beam rider acceleration command is modified to include an extra term. The beam-riding performance described above can thus be significantly improved by taking the beam motion into account. CLOS guidance is used mostly in shortrange air defense and antitank systems.

Both target tracking and missile tracking and control are performed manually. The operator watches the missile flight, and uses a signaling system to command the missile back into the straight line between operator and target (the "line of sight"). This is typically useful only for slower targets, where significant "lead" is not required. MCLOS is a subtype of command guided systems. In the case of glide bombs or missiles against ships or the supersonic Wasserfall against slow-moving B-17 Flying Fortress bombers this system worked, but as speeds increased MCLOS was quickly rendered useless for most roles.

Target tracking is automatic, while missile tracking and control is manual.

Target tracking is manual, but missile tracking and control is automatic. Is similar to MCLOS but some automatic system positions the missile in the line of sight while the operator simply tracks the target. SACLOS has the advantage of allowing the missile to start in a position invisible to the user, and is generally far easier to operate. SACLOS is the most common form of guidance against ground targets such as tanks and bunkers.

Target tracking, missile tracking and control are automatic.