Human female sexuality encompasses a broad range of behaviors and processes, including female sexual identity and sexual behavior, the physiological, psychological, social, cultural, political, and spiritual or religious aspects of sexual activity. Various aspects and dimensions of female sexuality, as a part of human sexuality, have also been addressed by principles of ethics, morality, and theology. In almost any historical era and culture, the arts, including literary and visual arts, as well as popular culture, present a substantial portion of a given society's views on human sexuality, which includes both implicit (covert) and explicit (overt) aspects and manifestations of feminine sexuality and behavior.

In most societies and legal jurisdictions, there are legal bounds on what sexual behavior is permitted. Sexuality varies across the cultures and regions of the world, and has continually changed throughout history, and this also applies to female sexuality. Aspects of female sexuality include issues pertaining to body image, self-esteem, personality, sexual orientation, values and attitudes, gender roles, relationships, activity options, and communication.

While most women are heterosexual, and attracted only to men, significant minorities are homosexual (lesbian) or varying degrees of bisexual. Bisexual females are more common than bisexual males.

Sexual activity can encompass various sexually stimulating factors (physiological stimulation or psychological stimulation), including sexual fantasies and different sex positions, or the use of sex toys. Foreplay may precede some sexual activities, often leading to sexual arousal of the partners. It is also common for people to be sexually satisfied by being kissed, touched erotically, or held.

Orgasm, or sexual climax, is the sudden discharge of accumulated sexual tension during the sexual response cycle, resulting in rhythmic muscular contractions in the pelvic region characterized by an intense sensation of pleasure. Women commonly find it difficult to experience orgasms during vaginal intercourse. Mayo Clinic states: "Orgasms vary in intensity, and women vary in the frequency of their orgasms and the amount of stimulation necessary to trigger an orgasm." Additionally, some women may require more than one type of sexual stimulation in order to achieve orgasm. Clitoral stimulation in normal copulation happens when the thrusting of the penis moves the clitoral hood and labia minora, extending from the clitoris.

Orgasm in women has typically been divided into two categories: clitoral and vaginal (or G-spot) orgasms. 70–80% of women require direct clitoral stimulation to achieve orgasm, though indirect clitoral stimulation may also be sufficient. Clitoral orgasms are easier to achieve because the glans of the clitoris, or clitoris as a whole, has more than 8,000 sensory nerve endings, which is as many (or more in some cases) nerve endings as are present in the human penis or glans penis. As the clitoris is homologous to the penis, it is the equivalent in its capacity to receive sexual stimulation.

Although orgasms by vaginal stimulation are more difficult to achieve, the G-spot area may produce an orgasm if properly stimulated. The G-spot's existence, and existence as a distinct structure, is still under dispute, as its reported location can vary from woman to woman, appears to be nonexistent in some women, and it is hypothesized to be an extension of the clitoris and therefore the reason for orgasms experienced vaginally.

Women are able to achieve multiple orgasms due to the fact that they generally do not require a refractory period like men do after the first orgasm. Although it is reported that women do not experience a refractory period and thus can experience an additional orgasm, or multiple orgasms, soon after the first orgasm, some sources state that both men and women experience a refractory period because, due to clitoral hypersensitivity or sexual satisfaction, women may experience a very small period after orgasm in which further sexual stimulation does not produce excitement.