The French and Indian War, 1754 to 1763, was a conflict in North America between Great Britain and France, along with their respective Native American allies. Historians generally consider it part of the global conflict 1756 to 1763 Seven Years' War, although in the United States it is often viewed as a distinct conflict unassociated with any larger European war.

Although Britain and France were officially at peace following the Treaty of Aix-la-Chapelle in 1748, tensions over trade continued in North America, which culminated in a dispute over the Forks of the Ohio, and the related French Fort Duquesne which controlled them. In May 1754, this led to the Battle of Jumonville Glen, when Virginia militia led by George Washington ambushed a French patrol.

In 1755, Edward Braddock, the new Commander-in-Chief, North America, planned a four-way attack on the French. None succeeded, while the Braddock Expedition ended in disaster at the Battle of the Monongahela on July 9, 1755, with Braddock himself dying of his wounds a few days later. From 1755 to 1757, further British operations in Pennsylvania and New York failed, but were offset by the British capture of Fort Beauséjour on the border between British Nova Scotia and French Acadia. Over the next nine years, French settlers were expelled and replaced by those from New England.

The Seven Years' War began in 1756, and a number of disastrous campaigns in 1757, including the Louisbourg Expedition (1757) and Siege of Fort William Henry led to the fall of the British government. The new Prime Minister, William Pitt significantly increased British military resources in the colonies when France was struggling to support their limited forces in New France, preferring to concentrate their forces in Europe. Between 1758 and 1760, the British launched a campaign to capture French Canada, taking Quebec in 1759, then Montreal the following year. This largely ended fighting in North America.

In accordance with the Treaty of Paris (1763), France ceded its Canadian possessions to Britain, along with its claim to territories east of the Mississippi River. France also gave Spain French Louisiana west of the Mississippi River in compensation for their loss of Spanish Florida to Britain. The French presence in North America was reduced to the islands of Saint Pierre and Miquelon, confirming Britain's position as the dominant colonial power.

In British America, wars were often named after the sitting British monarch, such as King William's War or Queen Anne's War. There had already been a King George's War in the 1740s during the reign of King George II, so British colonists named this conflict after their opponents, and it became known as the French and Indian War. This continues as the standard name for the war in the United States, although indigenous peoples fought on both sides of the conflict. It also led into the Seven Years' War overseas, a much larger conflict between France and Great Britain that did not involve the American colonies; some historians make a connection between the French and Indian War and the Seven Years' War overseas, but most residents of the United States consider them as two separate conflicts—only one of which involved the American colonies, and American historians generally use the traditional name. Less frequently used names for the war include the Fourth Intercolonial War and the Great War for the Empire.

In Europe, the French and Indian War is conflated into the Seven Years' War and not given a separate name. "Seven Years" refers to events in Europe, from the official declaration of war in 1756—two years after the French and Indian War had started—to the signing of the peace treaty in 1763. The French and Indian War in America, by contrast, was largely concluded in six years from the Battle of Jumonville Glen in 1754 to the capture of Montreal in 1760. Canadians conflate both the European and American conflicts into the Seven Years' War (Guerre de Sept Ans). French Canadians also use the term "War of Conquest" (Guerre de la Conquête), since it is the war in which New France was conquered by the British and became part of the British Empire. In Quebec, this term was promoted by popular historians Jacques Lacoursière and Denis Vaugeois, who borrowed from the ideas of Maurice Séguin in considering this war as a dramatic tipping point of French Canadian identity and nationhood.

At this time, North America east of the Mississippi River was largely claimed by either Great Britain or France. Large areas had no colonial settlements. The French population numbered about 75,000 and was heavily concentrated along the St. Lawrence River valley, with some also in Acadia (present-day New Brunswick and parts of Nova Scotia), including Île Royale (Cape Breton Island). Fewer lived in New Orleans; Biloxi, Mississippi; Mobile, Alabama; and small settlements in the Illinois Country, hugging the east side of the Mississippi River and its tributaries. French fur traders and trappers traveled throughout the St. Lawrence and Mississippi watersheds, did business with local Indian tribes, and often married Indian women. Traders married daughters of chiefs, creating high-ranking unions.