Gobiconodon is an extinct genus of carnivorous mammals (or possibly non-mammalian mammaliaforms) belonging to the family Gobiconodontidae. Undisputed records of Gobiconodon are restricted to the Early Cretaceous of Asia and North America, but isolated teeth attributed to the genus have also been described from formations in England and Morocco dating as far back as the Middle Jurassic. Species of Gobiconodon varied considerably in size, with G. ostromi, one of the larger species, being around the size of a modern Virginia opossum. Like other gobiconodontids, it possessed several speciations towards carnivory, such as shearing molariform teeth, large canine-like incisors and powerful jaw and forelimb musculature, indicating that it probably fed on vertebrate prey. Unusually among predatory mammals and other eutriconodonts, the lower canines were vestigial, with the first lower incisor pair having become massive and canine-like. Like the larger Repenomamus there might be some evidence of scavenging.

In 1978, the species Gobiconodon borissiaki and Guchinodon hoburensis were described by the Soviet palaeontologist B. A. Trofimov, based on remains from the Khoboor beds (Dzunbain Formation) of the Mongolian Gobi Desert, which date to the Aptian to Albian ages of the Early Cretaceous. The specimens were found during a 1969–1973 Soviet-Mongolian palaeontological expedition to the area. The Gobiconodon borissiaki material consisted of the holotype, a partial right dentary bone, and fragments of eight other dentaries and two maxillae. Guchinodon hoburensis was represented only by its holotype, a single partial right dentary. Later expeditions to the area have found several more jaw fragments of both species. In 1998, Guchinodon hoburensis was reassigned to Gobiconodon by Kielan-Jaworowska and Dashzeveg, making Guchinodon a junior synonym of that genus.

Gobiconodon ostromi, from the Aptian–Albian Cloverly Formation of the US state of Montana, was described in 1988 by Farish A. Jenkins and Charles R. Schaff. It is represented by two partial skeletons preserving both cranial and postcranial elements. The holotype, MCZ 19965, consists of both sides of the dentary, as well as several postcranial bones. The referred specimen MCZ 19860 contains both sides of the dentary and parts of the upper jaw, cranium, vertebrae, ribs, shoulders, pelvis and limbs. The specific epithet honours the American palaeontologist John Ostrom for his studies on the Cloverly Formation.

Gobiconodon hopsoni, from the Early Cretaceous (Berriasian–Barremian) Öösh Formation of Mongolia, was described in 2001 by Guillermo W. Rougier, Michael J. Novacek, Malcolm McKenna and John R. Wible. The holotype, PSS-MAE 140, consists of a partial right maxilla preserving the fourth molariform and parts of the second and third molariforms. The referred specimen PSS-MAE 139 consists of a part of the right dentary bone preserving an unerupted molariform and sockets for two other teeth. Two additional specimens from the same locality, both represented by dentary fragments, were at first described merely as Gobiconodon sp., but not assigned to any species. The specimens were eventually assigned to G. hopsoni in a 2015 paper by Alexey Lopatin and Alexander Averianov. The species is named after the palaeontologist James A. Hopson.

Gobiconodon palaios, from the Early Cretaceous (possibly Berriasian) of Morocco, was described in 2003 by Denise Sigogneau-Russell. It is based on isolated upper molariforms and possible premolariforms. The molariforms were assigned to the genus Gobiconodon due to their slightly triangulated cusp arrangement. According to Lopatin & Averianov (2015), this feature is not unique to this genus, but is also found in other genera like Repenomamus and the "amphilestid" Juchilestes. According to these authors, G. palaios may be synonymous with Kryptotherium polysphenos, another species found at the same locality, which is known only from lower teeth.

Gobiconodon zofiae was described in 2003 by Li Chuankui, Wang Yuanqing, Hu Yaoming and Meng Jin. The holotype, IVPP V12585, is based on a single skull and lower jaw found near the village of Lujiatun in the province of Liaoning in Northeast China. The rocks in which the species was found belong to the basal member of the Yixian Formation, and have been dated to the Barremian age of the Early Cretaceous. The species is named after the Polish palaeontologist Zofia Kielan-Jaworowska. According to Lopatin & Averianov (2015), G. zofiae possesses no features clearly distinguishing it from G. hopsoni of Mongolia, but they provisionally retained it as a valid taxon until more material of the two species is discovered.

Gobiconodon luoianus was described in 2009 by Yuan Chongxi, Xu Li, Zhang Xingliao, Xi Yunhong, Wu Yanhua and Ji Qiang based on material found near Lujiatun, in the same member of the Yixian Formation that yielded G. zofiae. It is known from a single specimen, 41H III-0320, consisting of a nearly complete skull with well-preserved upper and lower teeth. The species is named after the Chinese palaeontologist Zhe-Xi Luo. Lopatin & Averianov (2015) disputed the validity of this species, suggesting that it represents a junior synonym of G. zofiae.

Gobiconodon haizhouensis and Gobiconodon tomidai were described in 2015 by Nao Kusuhashi, Wang Yuanqing, Li Chuankui and Jin Xun. Both species are from the Early Cretaceous (Aptian to Albian) of the Liaoning province of China. G. haizhouensis is known from a single specimen (IVPP V14509) from the Fuxin Formation, consisting of a nearly complete right dentary. The species is named after Haizhou, an old name for the town of Fuxin where the type specimen was found. Lopatin (2017) commented that G. haizhouensis has no valid characteristics distinguishing it from the Mongolian species G. hoburensis, but did not formally synonymise the two.