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IUPAC Color Books
IUPAC Color Books
IUPAC Color Books
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The International Union of Pure and Applied Chemistry (IUPAC) publishes many books which contain its complete list of definitions. The definitions are divided initially into seven IUPAC Colour Books: Gold, Green, Blue, Purple, Orange, White, and Red.[1] There is also an eighth book, the "Silver Book".

Blue Book

[edit]
Main article: Nomenclature of Organic Chemistry

Nomenclature of Organic Chemistry, commonly referred to by chemists as the Blue Book, is a collection of recommendations on organic chemical nomenclature published at irregular intervals by the International Union of Pure and Applied Chemistry (IUPAC). A full edition was published in 1979,[2] an abridged and updated version of which was published in 1993 as A Guide to IUPAC Nomenclature of Organic Compounds.[3] Both of these are now out-of-print in their paper versions, but are available free of charge in electronic versions. After the release of a draft version for public comment in 2004[4] and the publication of several revised sections in the journal Pure and Applied Chemistry, a fully revised version was published in print in 2013.[5][2]

Gold Book

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The front cover of the second edition of the Compendium of Chemical Terminology.

The Compendium of Chemical Terminology is a book published by the International Union of Pure and Applied Chemistry (IUPAC) containing internationally accepted definitions for terms in chemistry. Work on the first edition was initiated by Victor Gold, thus spawning its informal name: the Gold Book.

The first edition was published in 1987 (ISBN 0-63201-765-1) and the second edition (ISBN 0-86542-684-8), edited by A. D. McNaught and A. Wilkinson, was published in 1997. A slightly expanded version of the Gold Book is also freely searchable online. Translations have also been published in French, Spanish and Polish.

Green Book

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Main article: Quantities, Units and Symbols in Physical Chemistry

Quantities, Units and Symbols in Physical Chemistry, commonly known as the Green Book, is a compilation of terms and symbols widely used in the field of physical chemistry. It also includes a table of physical constants, tables listing the properties of elementary particles, chemical elements, and nuclides, and information about conversion factors that are commonly used in physical chemistry. The most recent edition is the third edition (ISBN 978-0-85404-433-7), originally published by IUPAC in 2007. A second printing of the third edition was released in 2008; this printing made several minor revisions to the 2007 text. A third printing of the third edition was released in 2011. The text of the third printing is identical to that of the second printing.

Orange Book

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Main article: Compendium of Analytical Nomenclature

The Compendium of Analytical Nomenclature is a book published by the International Union of Pure and Applied Chemistry (IUPAC) containing internationally accepted definitions for terms in analytical chemistry. It has traditionally been published in an orange cover, hence its informal name, the Orange Book.

Although the book is described as the "Definitive Rules", there have been three editions published; the first in 1978 (ISBN 0-08022-008-8), the second in 1987 (ISBN 0-63201-907-7) and the third in 1998 (ISBN 0-86542-615-5). The third edition is also available online. A Catalan translation has also been published (1987, ISBN 84-7283-121-3).

Purple Book

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Main article: Compendium of Macromolecular Nomenclature

The first edition of the Compendium of Macromolecular Terminology and Nomenclature, known as the Purple Book, was published in 1991. It is about the nomenclature of polymers. The second and latest edition was published in December 2008[6] and is also available for download.[7]

Red Book

[edit]
Main article: Nomenclature of Inorganic Chemistry

Nomenclature of Inorganic Chemistry, by chemists commonly referred to as the Red Book, is a collection of recommendations on inorganic chemical nomenclature. It is published at irregular intervals by the International Union of Pure and Applied Chemistry (IUPAC). The last full edition was published in 2005,[8] in both paper and electronic versions.

Published editions
Release year Title Publisher ISBN
2005 Recommendations 2005 (Red Book) RSC Publishing 0-85404-438-8
2001 Recommendations 2000 (Red Book II)
(supplement) 		0-85404-487-6
1990 Recommendations 1990 (Red Book I) Blackwell 0-632-02494-1
1971 Definitive Rules 1970 [9] Butterworth 0-408-70168-4
1959 1957 Rules -
1940/1941 1940 Rules Scientific journals

Silver Book

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The IUPAC also publishes a Silver Book, not listed with the other "colour books", titled Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences.[10]

White Book

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The Biochemical Nomenclature and Related Documents (1992) or White Book contains definitions pertaining to biochemical research compiled jointly by IUPAC and the International Union of Biochemistry and Molecular Biology.

See also

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References

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[edit]
Revisions and contributorsEdit on WikipediaRead on Wikipedia

IUPAC Color Books

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The IUPAC Color Books are a series of authoritative publications issued by the International Union of Pure and Applied Chemistry (IUPAC), serving as the primary global standards for , , and symbols across various sub-disciplines of chemistry. These color-coded volumes, drafted by international teams of experts and ratified by IUPAC's Interdivisional Committee on , , and Symbols (ICTNS), establish precise rules and recommendations to ensure consistency in scientific communication, documentation, and education. The series encompasses eight main books, each distinguished by a unique color on its cover and focused on specific aspects of chemical practice. For instance:
  • Green Book: Quantities, Units and Symbols in Physical Chemistry, which defines conventions for physical quantities, units, and symbols used in and related fields.
  • Red Book: Nomenclature of Inorganic Chemistry, providing systematic naming rules for inorganic compounds and coordination entities.
  • Blue Book: Nomenclature of Organic Chemistry, outlining the preferred IUPAC names and structural representations for organic substances.
  • Purple Book: Compendium of Polymer Terminology and Nomenclature, standardizing terms for polymers and macromolecular chemistry.
  • Orange Book: Compendium of Terminology in Analytical Chemistry, covering definitions and recommendations for methods and procedures.
  • Silver Book: Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences, addressing terminology for properties measured in clinical settings.
  • White Book: Biochemical Nomenclature and Related Documents, compiling symbols and for biochemical entities like enzymes and carbohydrates.
  • Gold Book: Compendium of Chemical Terminology (online edition), offering concise definitions for over 7,000 chemical terms as a general reference.
In addition to these, the Principles of Chemical Nomenclature (first published in 1998 and revised in 2011) serves as a foundational guide synthesizing key principles from the Color Books. The books are periodically updated to reflect advances in chemical science, ensuring their relevance for researchers, educators, and policymakers worldwide.

Overview

Definition and Purpose

The IUPAC Color Books constitute a set of eight color-coded publications produced by the International Union of Pure and Applied Chemistry (IUPAC), serving as the authoritative global resources for , , and symbols across various subfields of chemistry. These volumes establish internationally accepted standards for naming chemical compounds, defining key terms, and employing symbols, thereby promoting clarity, consistency, and precision in scientific communication, education, and practice. The development of these books involves drafting by international committees of experts in specific chemistry disciplines, followed by rigorous ratification by IUPAC's Interdivisional Committee on Terminology, Nomenclature, and Symbols (ICTNS), which ensures alignment with global scientific consensus through extensive review and approval processes. This structured approach guarantees that the standards are robust, adaptable, and widely applicable. The series comprises the following volumes, each addressing a distinct aspect of chemical : In contemporary chemistry, the Color Books play a pivotal role in enabling interdisciplinary collaboration by standardizing language across subfields.

History and Development

The International Union of Pure and Applied Chemistry (IUPAC) was established in 1919 by chemists from academia and industry in response to the disruptions caused by , aiming to foster international cooperation and standardize chemical practices, including . This foundation addressed the need for unified terminology amid fragmented national standards, leading to initial efforts in the and through commissions focused on organic and inorganic naming conventions. These early initiatives laid the groundwork for systematic chemical language, emphasizing consistency in reporting compounds and reactions across borders. The tradition of color-coding for IUPAC publications emerged in the mid-20th century to differentiate specialized resources, with the first Red Book on inorganic published in 1958 as a comprehensive guide to naming inorganic compounds. This approach facilitated quick identification among growing outputs, exemplified by the Green Book's origins in 1969 as a manual for physicochemical quantities and units. By the 1970s, the Interdivisional Committee on Terminology, , and Symbols (ICTNS) was formed in 1977 to coordinate terminology oversight across IUPAC divisions, ensuring cohesive development of standards. The development process for the Color Books involves drafting by relevant IUPAC divisions or task groups, followed by rigorous and public consultation, with final recommendations published in the journal Pure and Applied Chemistry. Periodic revisions incorporate scientific advances, such as those from , to maintain relevance. Recent updates include the release of an updated Blue Book in 2024, a new abridged version of the Green Book in 2025, and revisions to the Gold Book in 2024. A key milestone was the 2011 publication of Principles of , edited by G.J. Leigh, serving as an introductory overview to the series and synthesizing core guidelines. In the and , the series transitioned to digital formats for broader accessibility, with full online availability on the IUPAC website beginning in the late 1990s and interactive features added, such as searchable databases in the Gold Book by 2006. Ongoing challenges include addressing nomenclature gaps in emerging fields like , prompting targeted updates and provisional recommendations to integrate new materials and concepts.

General and Physical Chemistry Resources

Gold Book

The IUPAC Gold Book, formally titled the Compendium of Chemical Terminology (IUPAC Recommendations), serves as the central glossary for chemical terminology, compiling authoritative definitions drawn from IUPAC recommendations across all subdisciplines of chemistry. It provides an alphabetical arrangement of over 7,000 terms, encompassing preferred IUPAC names, deprecated terminology, and cross-references to related concepts, ensuring standardized language for scientific communication. As part of the IUPAC Color Books series, it integrates definitions from other volumes, such as symbols and quantities from the Green Book, while focusing on broad terminological clarity rather than specialized rules. The publication originated with the first edition in 1987, initiated and edited by Victor Gold, whose contributions led to the book's popular name. A second edition followed in 1997, edited by A. D. McNaught and A. Wilkinson and published by Blackwell , expanding the with refined definitions sourced from IUPAC's Pure and Applied Chemistry. The online version was launched in 1997, evolving through an XML format from 2005 and a dynamic platform in 2019 under IUPAC Project 2016-046-1-024, with annual updates incorporating new entries, such as over 500 added by contributor Aubrey Jenkins. As of 2025, the online edition is version 5.0.0, featuring 2024 updates including a revised metadata model and new terms such as the definition of materials chemistry. This digital iteration, hosted at goldbook.iupac.org, functions as a searchable database with DOI-linked citations to original recommendations, facilitating easy access and verification. Key features include detailed definitions often accompanied by usage notes and references to source documents, covering categories such as physical properties, reaction types, and spectroscopic terms. For instance, entries on briefly reference conventions from the Blue Book or Red Book without delving into structural details. The Gold Book's unique role as a "living document" is supported by community-submitted feedback, directed to technical editor Stuart , enabling ongoing revisions aligned with evolving IUPAC standards and ensuring its relevance in a digital era through extensible formats like XML and an API for machine-readable content.

Green Book

The IUPAC Green Book, formally titled Quantities, Units and Symbols in Physical Chemistry, serves as a standardized reference for the nomenclature, symbols, and units used in , promoting clarity and consistency in scientific communication across disciplines. It provides definitions and recommendations for physical quantities, aligning with the (SI) and guidelines from organizations such as the (ISO), the International Union of Pure and Applied Physics (IUPAP), and the Bureau International des Poids et Mesures (BIPM). The book emphasizes precision in measurements and reporting, offering practical guidance to avoid ambiguity in interdisciplinary research. The Green Book originated from the 1969 Manual of Symbols and Terminology for Physicochemical Quantities and Units, which laid the groundwork for standardizing physicochemical terminology. The first edition under the current title appeared in 1988, followed by a second edition in 1993, a third edition in 2007 (with reprints in 2008 and 2011 incorporating minor corrections), and an abridged fourth edition in 2023 published by the Royal Society of Chemistry, with a free PDF version released in March 2025. A for a digitally native fifth edition is ongoing as of 2025. These updates reflect evolving international standards and incorporate new developments in fields like . In scope, the Green Book covers base physical quantities such as (n, in mol), length (l, in m), (m, in kg), time (t, in s), and (U, in J), along with derived quantities in (e.g., H, S, Gibbs energy G), (e.g., rate constant k, v), and (e.g., electric potential difference E, ). It includes sections on (e.g., wavefunction ψ, energy E_h), molecular , solid-state properties, statistical , and , ensuring comprehensive applicability to modern . Key features include extensive tables of recommended symbols—for instance, p for and μ for —along with guidelines for printing conventions, such as using italic fonts for physical quantities (p, μ) and roman fonts for units (Pa, J mol⁻¹) and symbols. These tables facilitate printable reference lists, while appendices provide unit conversion factors, fundamental constants, and uncertainty reporting protocols to support precise experimental work. Unlike broader definitional resources, the Green Book uniquely focuses on quantitative standardization, with updates addressing emerging areas like , and all editions are freely available as PDFs on the IUPAC website.

Organic and Inorganic Nomenclature

Blue Book

The Blue Book, formally titled Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred IUPAC Names 2013, establishes standardized rules for naming organic compounds to ensure unambiguous communication in scientific, industrial, and regulatory contexts. It focuses on generating systematic names based on molecular structure, prioritizing preferred IUPAC names (PINs) for unique identification while permitting retained traditional names for common compounds, such as acetic acid for CH₃COOH. This approach supports clarity in describing diverse organic structures, from simple hydrocarbons to complex assemblies. The publication history traces back to the first comprehensive edition in 1979, which consolidated sections on hydrocarbons, heterocyclic systems, and characteristic groups into a single volume published by . An abridged and updated version followed in 1993 as A Guide to IUPAC Nomenclature of Organic Compounds, streamlining rules for broader accessibility. The 2013 edition, prepared by Henri A. Favre and Warren H. Powell and issued by the Royal Society of Chemistry in four volumes, represents a major revision incorporating PINs and expanding coverage, with an online and PDF version released in 2014 and updated through 2023. Ongoing supplements appear in Pure and Applied Chemistry, addressing evolving nomenclature needs. In scope, the Blue Book provides detailed rules for naming hydrocarbons, functional groups, stereochemistry, and basic polymer structures, emphasizing substitutive nomenclature as the primary method—selecting a parent chain or ring, adding suffixes for principal functions (e.g., -ol for alcohols), and prefixes for substituents with locants (e.g., 2-methylpropane for (CH₃)₂CHCH₃). It includes guidelines for isotopes (e.g., using nuclide symbols like ¹⁴C), radicals (e.g., naming alkyl radicals as suffixes like -yl), and assemblies of molecules, alongside stereodescriptors for chiral centers and double bonds. Key features encompass hierarchical selection criteria for parent structures and comprehensive indexing of functional groups, facilitating name construction for multifaceted compounds. Unique aspects address contemporary challenges, such as for s (e.g., C₆₀-[5,6] as a von Baeyer system extension) and phane nomenclature for assemblies, while integrating organic components of organometallics with brief cross-references to inorganic rules. The framework supports online tools for automated name generation, essential for complex pharmaceutical names like (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid for amoxicillin. These elements ensure adaptability to emerging structures without compromising systematic rigor.

Red Book

The Red Book, formally titled Nomenclature of Inorganic Chemistry (IUPAC Recommendations), provides a standardized for naming inorganic compounds, emphasizing systematic approaches to ensure unambiguous communication in chemical and practice. It focuses on constructing names and formulas for a wide array of inorganic entities, drawing on principles that align with broader IUPAC while prioritizing the unique structural features of inorganic s. This resource is essential for chemists dealing with coordination chemistry, where complex assemblies of metals and ligands predominate, and it serves as the authoritative guide for generating preferred names in inorganic contexts. The publication history of the Red Book traces back to early efforts by the IUPAC Commission on the Nomenclature of , with the earliest set of rules appearing in 1940 within Pure and Applied Chemistry. Tentative rules followed in 1957, leading to the first definitive edition, Definitive Rules for the Nomenclature of Inorganic Chemistry, published in 1959. Subsequent revisions culminated in the 1971 definitive rules, the 1990 edition (known as Red Book I), the 2000 supplementary volume (Red Book II), and the comprehensive 2005 edition, published by the Royal Society of Chemistry, which supersedes prior versions and incorporates updates reflecting advances in inorganic synthesis and characterization. As of 2025, a revision of the Red Book is in progress, incorporating ongoing projects such as updates to kappa notation for coordination entities, though no new edition has been released. A concise brief guide to its principles was issued in 2015 to aid practical application. In scope, the Red Book addresses nomenclature for elements, ions (including monoatomic and polyatomic species), coordination compounds, and organometallic compounds, employing additive nomenclature—where names assemble from a central atom and surrounding ligands—and substitutive nomenclature, which treats parent hydrides as bases for substitution. It extends to solid-state compounds, such as polymorphs and non-stoichiometric phases described via Pearson symbols, and cluster compounds like using structural descriptors (e.g., nido- or closo-). For hybrid organic-inorganic systems, it briefly references organic ligand naming from the Blue Book to maintain consistency, without delving into organic parent chains. Key features include detailed rules for denoting oxidation states using Roman numerals in parentheses (e.g., copper(II) oxide), specifying stereoisomers in coordination complexes via geometrical descriptors like cis- or trans-, and isotopic modifications with mass numbers or nuclide symbols (e.g., [²H₆]SiCl₂). The volume contains extensive tables of ligand names, abbreviations, and formulas (e.g., Tables VII–X for coordination ligands), along with flowcharts to select appropriate nomenclature types. Unique to inorganic contexts, it covers nomenclature for polynuclear clusters and solid-state materials, and its principles have been applied to name newly discovered superheavy elements post-2016, such as nihonium (element 113), using systematic extensions like "nihonide" for the anion. These elements ensure the Red Book remains adaptable to emerging discoveries while distinguishing inorganic naming from physical property notations in the Green Book or organic skeletal rules in the Blue Book.

Macromolecular and Biochemical Nomenclature

Purple Book

The Purple Book, formally titled Compendium of Polymer Terminology and Nomenclature (IUPAC Recommendations 2008), serves as the primary IUPAC resource for standardizing terminology and nomenclature in polymer science, facilitating unambiguous communication among researchers, industry professionals, and educators worldwide. It compiles key recommendations on naming conventions, definitions, and symbols for various polymer types, emphasizing systematic approaches to describe molecular structures and properties. The compendium addresses both synthetic and natural polymers, including linkages to nomenclature for biopolymers like DNA, while integrating an online glossary that cross-references terms with the IUPAC Gold Book for broader chemical consistency. Publication history traces back to foundational recommendations, such as the 1985 source-based for copolymers and basic definitions of terms, which formed the groundwork for the first full edition in 1991 as the *Compendium of Macromolecular . A comprehensive update followed in 1993 with guidelines for regular double-strand , leading to the second edition in 2009 (based on 2008 recommendations), which expanded to 22 chapters covering single-strand, double-strand, and irregular structures. Subsequent supplements include the 2014 recommendations on terms for individual macromolecules, assemblies, and solutions, and the 2020 concise guide to for authors, ensuring ongoing relevance amid advances in . The scope encompasses structure-based and source-based naming systems: source-based nomenclature derives names from monomer origins (e.g., poly(styrene) from styrene), while structure-based focuses on the constitutional repeating unit (CRU), the smallest repeating structural segment oriented to show end-bond directionality, as in poly(oxy-1,4-phenylenecarbonyl) for a . It defines terms for processes (e.g., vs. ), configurations (e.g., linear, branched, or cyclic), and properties (e.g., molecular weight distribution), with dedicated chapters on —such as isotactic (regular ) versus syndiotactic arrangements—and irregular structures like random copolymers. Key features include illustrative diagrams for chain representations, enabling visualization of complex architectures, and rules for abbreviations that promote brevity in scientific literature without sacrificing precision. These elements extend general organic principles, such as naming from the Blue Book, to macromolecular scales.

White Book

The White Book, formally titled Biochemical Nomenclature and Related Documents, is a compendium of recommendations developed by the IUPAC-IUBMB on Biochemical (JCBN) in collaboration with the Nomenclature Committee of the International Union of Biochemistry and (IUBMB). It establishes standardized terminology for key areas in biochemistry to ensure consistent communication across scientific disciplines. The document addresses the naming of enzymes, coenzymes, metabolites, and other biomolecules, including rules for carbohydrates, , and . The publication history traces back to the initial efforts in , with the formation of the IUB Enzyme Commission in 1956, leading to the first formal recommendations in 1961. A comprehensive compilation appeared in 1975, followed by a 1978 reprint, and the second edition was published in 1992 by Portland Press. Subsequent updates have focused on the list, with significant revisions in 1992 and 2018, including the addition of a seventh enzyme class for translocases to reflect advances in understanding membrane transport. Although the printed White Book from 1992 is out of print, its content is maintained and expanded through online resources integrated with broader IUPAC terminology efforts, such as the Gold Book for physical and general chemical terms. The scope encompasses systematic naming conventions, particularly for enzymes via Enzyme Commission (EC) numbers, which classify reactions into hierarchical categories: oxidoreductases (EC 1), transferases (EC 2), hydrolases (EC 3), lyases (EC 4), isomerases (EC 5), ligases (EC 6), and translocases (EC 7). For instance, EC 1.1.1.1 designates , highlighting the enzyme's role in oxidizing alcohols using NADP+ as a cofactor. Key features include symbolism for reaction mechanisms, such as arrows denoting proton transfers or bond formations, and comprehensive lists of accepted names, synonyms, and catalytic activities to avoid ambiguity. The nomenclature also covers coenzymes like NAD+ and metabolites, alongside specific rules for biomolecular structures, ensuring compatibility with bioinformatics databases for and genomic studies. A distinctive aspect of the White Book is its joint IUPAC-IUBMB framework, tailored to the interdisciplinary needs of life sciences by incorporating nomenclature for post-translational modifications in proteins, such as or , and extending to nucleic acids and . This collaborative approach promotes global standardization, facilitating research in enzymology, metabolism, and while addressing evolving discoveries in molecular mechanisms.

Analytical and Clinical Terminology

Orange Book

The Orange Book, formally titled the Compendium of Terminology in Analytical Chemistry, serves as the authoritative IUPAC resource for standardized definitions and recommendations in analytical chemistry. First published in 1978, it originated from efforts by the IUPAC Commission on Analytical Nomenclature to consolidate terms from reports spanning 1971 to 1975, addressing the need for unified language amid evolving analytical methods. Subsequent editions include the second in 1987, incorporating updates from 1976 to 1984; the third in 1997 by Blackwell Science; and the fourth in 2023 by the Royal Society of Chemistry, reflecting advancements in automation, instrumentation, and interdisciplinary applications. Digital versions and ongoing revisions have been hosted on IUPAC platforms since the 2010s, ensuring accessibility and timeliness. The scope encompasses definitions for core analytical processes, including separation techniques such as and , spectroscopic methods like atomic absorption and , and instrumental approaches such as . It also covers sampling strategies, , and emerging areas like and bio-analytical procedures, extending beyond mere to include structural characterization, , and temporal variations in samples. Recommendations address method validation, error analysis, and , aligning with international standards from ISO and JCGM for metrological and performance criteria. Physical units relevant to analysis draw briefly from the Green Book for consistency in notation. Key features include precise definitions of critical terms, such as "limit of detection" (the lowest analyte amount reliably distinguishable from noise) and "selectivity" (the ability to differentiate the analyte from interferents), which facilitate unambiguous communication in research and industry. Guidelines emphasize standardized reporting of results, including uncertainty estimation using approaches like the GUM framework, and provide protocols for expressing precision, accuracy, and trueness in quantitative analysis. The compendium features tables of common abbreviations (e.g., LOD for limit of detection, RSD for relative standard deviation) and symbols, promoting interoperability across laboratories. Unique to the Orange Book is its focus on quality assurance in diverse settings, from environmental monitoring to pharmaceutical testing, with updates incorporating techniques like hyphenated methods (e.g., GC-MS) to support modern analytical workflows.

Silver Book

The Silver Book, formally titled Compendium of Terminology and Nomenclature of Properties in Clinical Laboratory Sciences (IUPAC/IFCC Recommendations), provides standardized terminology for properties measured in clinical laboratory sciences. First published in 1995 as a joint effort between the International Union of Pure and Applied Chemistry (IUPAC) and the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC), it aimed to harmonize nomenclature for clinical reports and data exchange. The second edition, released in 2017 (with recommendations dated 2016), extensively updated the content to reflect advances in and clinical practice, incorporating input from experts like G. Férard, R. Dybkaer, and X. Fuentes-Arderiu. It is published by the Royal Society of Chemistry and supported by online resources, including a concise summary and project details for ongoing integration. The scope encompasses definitions for clinical analytes, such as blood glucose, along with measurement procedures and quality specifications essential for diagnostic accuracy. It addresses nomenclature for diagnostic properties across fields like allergology, haematology, , , , , , , haemostasis, and . This includes standardized kinds-of-quantity, for example mass concentration (e.g., in grams per liter for analytes), to ensure consistent reporting. Guidelines cover reference intervals—ranges of values considered normal for populations—and metrological traceability to Système International (SI) units, promoting reliable comparisons across laboratories. Tables within the compendium list clinical measurands, detailing their properties and units for practical application. A distinctive feature is its role in bridging chemistry and by aligning chemical with clinical needs, such as in systems for interoperable . It emphasizes the , Properties, and Units (NPU) system, which structures terms as "system-component; kind-of-quantity," to enhance clarity in reports. Examples include assays in (e.g., for drug concentrations) and (e.g., levels), where ensures diagnostic validity. While it complements analytical methods for clinical samples outlined in , the Silver Book uniquely focuses on property-specific terminology for diagnostics.

References

  1. https://iupac.org/what-we-do/books/color-books/
  2. https://iupac.org/what-we-do/books/greenbook/
  3. https://iupac.org/what-we-do/books/redbook/
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  22. https://old.iupac.org/publications/books/gbook/green_book_2ed.pdf
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  30. https://www.acdlabs.com/resources/iupac-blue-book/
  31. https://iupac.org/wp-content/uploads/2016/07/Red_Book_2005.pdf
  32. https://pubs.acs.org/doi/10.1021/cen-v068n052.p022a
  33. https://iupac.org/wp-content/uploads/2018/05/Inorganic-Brief-Guide-V1-3.pdf
  34. https://iupac.org/project/2025-006-1-800
  35. https://iupac.org/wp-content/uploads/2016/07/ONLINE-IUPAC-PB2-Online-June2014.pdf
  36. https://iupac.org/who-we-are/divisions/stp-history/
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  38. https://iupac.qmul.ac.uk/bibliog/white.html
  39. https://iubmb.org/about/committees/biochemical-nomenclature-committees/
  40. https://iubmb.qmul.ac.uk/enzyme/history.html
  41. https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.12530
  42. https://iubmb.org/wp-content/uploads/sites/10116/2018/11/A-Brief-Guide-to-Enzyme-Classification-and-Nomenclature-rev.pdf
  43. https://iubmb.qmul.ac.uk/enzyme/
  44. https://febs.onlinelibrary.wiley.com/doi/10.1111/febs.16274
  45. https://media.iupac.org/publications/analytical_compendium/
  46. https://iupac.org/recommendation/compendium-of-terminology-and-nomenclature-of-properties-in-clinical-laboratory-sciences/
  47. https://iupac.org/wp-content/uploads/2020/04/Silverbook_concise-summary2017.pdf
  48. https://doi.org/10.1039/9781782622451
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