Hank Green was born in Indianapolis, Indiana, marking the beginning of a life characterized by intellectual curiosity and a passion for learning. His early years laid the foundation for his later pursuits in science, education, and creative endeavors. He is the younger brother of author John Green.

Together with his brother John, Hank launched the Vlogbrothers YouTube channel, initially as a year-long video correspondence project. This endeavor evolved into a dynamic platform for discussing a wide range of topics, from science and history to mental health and current events. The channel gained a massive following and fostered a passionate community known as 'Nerdfighters', united by their shared enthusiasm for knowledge and making the world a better place. Vlogbrothers videos significantly shaped the landscape of online education and communication.