Helen Murray Free, along with her husband Alfred Free, pioneered the development of dip-and-read diagnostic tests. These tests revolutionized medical diagnostics by providing a simple, rapid, and cost-effective method for detecting various substances in urine and other bodily fluids.

Clinistix, the first dip-and-read test for glucose in urine, was introduced. This groundbreaking product allowed people with diabetes to easily monitor their glucose levels at home, improving their management of the condition.

Building on the success of Clinistix, Helen and Alfred Free and their team developed a range of other dip-and-read tests for various conditions, including bilirubinuria (Bili-Labstix), proteinuria (Albustix), and ketonuria (Ketostix). These tests aided in the diagnosis and monitoring of kidney disease, urinary tract infections, and other metabolic disorders.

Helen Murray Free's work on dip-and-read tests significantly improved patient care by providing healthcare professionals and patients with rapid, convenient, and affordable diagnostic tools. These tests enabled earlier detection of diseases, better management of chronic conditions, and improved overall health outcomes.