Helen Murray Free co-authored over 200 scientific papers and articles throughout her career. These publications covered various aspects of diagnostic chemistry, including the development and application of dip-and-read tests.

Helen and Alfred Free co-authored 'Urinalysis in Laboratory Practice', a comprehensive textbook that became a standard reference for laboratory professionals and students. The book covered the principles, methods, and clinical significance of urinalysis.

Helen Murray Free also contributed to the literature on science education, writing articles and giving presentations on effective methods for teaching science and encouraging students to pursue careers in science.