The Ho Chi Minh Trail (Vietnamese: Đường mòn Hồ Chí Minh), also called Annamite Range Trail (Vietnamese: Đường Trường Sơn) was a logistical network of roads and trails that ran from North Vietnam to South Vietnam through the kingdoms of Laos and Cambodia. The system provided support, in the form of manpower and materiel, to the Viet Cong (or "VC") and the People's Army of Vietnam (PAVN), during the Vietnam War. Construction for the network began following the North Vietnamese invasion of Laos in July 1959. At the time it was believed to be the main supply route, however it later transpired that the Sihanouk Trail which ran through Cambodia was handling significantly more material.

It was named by the U.S. after the North Vietnamese leader Hồ Chí Minh. The origin of the name is presumed to have come from the First Indochina War, when there was a Viet Minh maritime logistics line called the "Route of Ho Chi Minh", and shortly after late 1960, as the present trail developed, Agence France-Presse (AFP) announced that a north–south trail had opened, and they named the corridor La Piste de Hồ Chí Minh, the 'Hồ Chí Minh Trail'. The trail ran mostly in Laos, and was called the Trường Sơn Strategic Supply Route (Đường Trường Sơn) by the communists, after the Vietnamese name for the Annamite Range, a major mountain range of central Vietnam. They further identified the trail as either West Trường Sơn (Laos) or East Trường Sơn (Vietnam). According to the U.S. National Security Agency's official history of the war, the trail system was "one of the great achievements of military engineering of the 20th century". The trail was able to effectively supply troops fighting in the south, an unparalleled military feat, given it was the site of the single most intense air interdiction campaign in history.

Parts of what became the trail had existed for centuries as primitive footpaths that enabled trade. The area through which the system meandered was among the most challenging in Southeast Asia: a sparsely populated region of rugged mountains 500–2,400 metres (1,500–8,000 ft) in elevation, triple-canopy jungle and dense tropical rainforests. Pre-First Indochina War, the routes were known as the "Southward March", "Eastward March", "Westward March", and "Northward March". During the First Indochina War the Việt Minh maintained north–south communications and logistics by expanding on this system of trails and paths, and called the routes the "Trans-West Supply Line" (running in south Vietnam, Cambodia, and Thailand) and the "Trans-Indochina Link" (running in north Vietnam, Laos, and Thailand).

In May 1958 PAVN and Pathet Lao forces seized the transportation hub at Tchepone, on Laotian Route 9. Laotian elections in May brought a right-wing government to power in Laos, increasing dependence on U.S. military and economic aid and an increasingly antagonistic attitude toward North Vietnam.

PAVN forces, alongside the Pathet Lao, invaded Laos on 28 July 1959, with fighting all along the border with North Vietnam against the Royal Lao Army (RLA). In September 1959, Hanoi established the 559th Transportation Group, headquartered at Na Kai, Houaphan province in northeast Laos close to the border. It was under the command of Colonel (later General) Võ Bẩm and established to improve and maintain a transportation system to supply the VC insurgency against the South Vietnamese government. Initially, the North Vietnamese effort concentrated on infiltration across and immediately below the Vietnamese Demilitarized Zone (DMZ) that separated the two Vietnams. The 559th Group "flipped" its line of communications to the west side of the Trường Sơn mountains.

By 1959, the 559th had 6,000 personnel in two regiments alone, the 70th and 71st, not including combat troops in security roles or North Vietnamese and Laotian civilian laborers. In the early days of the conflict the trail was used strictly for the infiltration of manpower. At the time, Hanoi could supply its southern allies much more efficiently by sea. In 1959 the North Vietnamese created Transportation Group 759, which was equipped with 20 steel-hulled vessels to carry out such infiltration.

After the initiation of U.S. naval interdiction efforts in coastal waters, known as Operation Market Time, the trail had to do double duty. Materiel sent from the north was stored in caches in the border regions that were soon retitled "Base Areas" (BA), which, in turn, became sanctuaries for VC and PAVN forces seeking respite and resupply after conducting operations in South Vietnam.

There were five large base areas in the panhandle of Laos (see map). BA 604 was the main logistical center during the war. From there, the coordination and distribution of men and supplies into South Vietnam's Military Region (MR) I and BAs further south was accomplished.