Hohner Musikinstrumente GmbH & Co. KG is a German manufacturer of musical instruments, founded in 1857 by Matthias Hohner (1833–1902). It is a subsidiary of Matth. Hohner AG. The roots of the Hohner firm are in Trossingen, Baden-Württemberg. Hohner has manufactured a wide range of instruments, such as harmonicas, kazoos, accordions, recorder flutes, melodicas, banjos, electric, acoustic, resonator and classical guitars, basses, mandolins and ukuleles (under the brand name Lanikai). Hohner is known mostly for its harmonicas.

From the 1940s through 1990s, the company also manufactured various electric/electronic keyboards. Especially in the 1960s and 1990s, they manufactured a range of innovative and popular electromechanical keyboard instruments; the cembalet, pianet, basset, guitaret, and clavinet. In the 1980s, several Casio synthesizers (such as the Casio HT-3000/Hohner KS61midi and the VZ-1/HS-2) were sold under the Hohner brand.

Nowadays, Hohner produces harmonicas, melodicas, accordions and recorder flutes.

Clock maker Matthias Hohner began crafting diatonic harmonicas in 1857, assisted by his wife and a single employee. 650 were made in the first year. Hohner harmonicas quickly became popular, and in his lifetime Matthias built the largest harmonica factory in the world. During the American Civil War, Matthias Hohner distributed harmonicas to family members in the United States who in turn gave them to the soldiers.

In the 1920s, Hohner began manufacturing chromatic harmonicas, which unlike the "standard" diatonic form can be played in any key. Famous harmonicist Borrah Minevitch claimed he sold his design for the chromatic harmonica to Hohner.

In 1964 Hohner released "The Beatles Harmonica Kit" which was sold in a blister package, much like most Hohner harmonicas nowadays, retailed for $2.95, and help what Hohner calls "bring about a new popularity upsurge of the Hohner harmonica on both sides of the Atlantic.".

Matthias Karl Hohner, son of Dipl.-Ing. Matthias Hohner [de] and a direct descendant in fourth generation and name bearer of the founder Matthias Hohner [de], was one of the last members of the Hohner dynasty involved in managing the family business, he worked since 1924 at the company and in 1965 he became the president till 1971 when he died. His son Matthias Francisco Hohner belonged to the first generation of direct descendants who did not enter into the family business. Many direct descendants of the founder are still active as members of the "Deutsches Harmonika Museum" and the "Hohner'sche Familienverein".

In 1989, a controlling interest in Hohner was acquired by Kunz-Holding GmbH & Co., a German wood products manufacturer. Kunz obtained 67 percent of the public firm, with the Hohner family retaining an 8 percent stake.