Ice Age: Collision Course is a 2016 American animated adventure comedy film produced by Blue Sky Studios. The fifth installment in the Ice Age film series, it was directed by Michael Thurmeier, and written by Michael Wilson, Michael Berg, and Yoni Brenner. Ray Romano, John Leguizamo, Denis Leary, Josh Peck, Simon Pegg, Seann William Scott, Jennifer Lopez and Queen Latifah reprise their roles from the previous films. In the film, Scrat is propelled into outer space in an abandoned spaceship during an attempt to bury his acorn and accidentally sends a giant asteroid towards Earth. Manny, the Herd and Buck must go on a life-or-death mission to find a way to fend it off.

The film premiered at the Sydney Film Festival on June 19, 2016, and was theatrically released in the United States on July 22 by 20th Century Fox. The film received generally negative reviews from critics and grossed $408 million against a $105 million production budget. A spin-off film, The Ice Age Adventures of Buck Wild, was released in 2022 on Disney+, while a sequel, Ice Age: Boiling Point, is scheduled for theatrical release in 2027.

After the events of the previous film, Peaches is engaged to marry a benign mammoth named Julian, but Manny disapproves of this as he finds Julian annoying and incapable of protecting her. The concern escalates when Peaches reveals her wish to travel and explore the world as their honeymoon, which both Manny and Ellie oppose. Diego and Shira want to have children but worry they will not make friends, as the other kids are scared of saber-tooth tigers. Sid is about to propose marriage to his girlfriend, Francine, but is dumped by her and laments his solitude.

During Manny and Ellie's wedding anniversary, asteroids strike the place, and the herd barely escapes and takes shelter in a cave. Meanwhile, in the underground lost world, Buck returns a Chasmosaurus egg to its mother after it was stolen by a trio of flying dromaeosaurs named Gavin, Gertie, and Roger. Buck discovers an ancient stone pillar and takes it to the surface, where he reunites with the herd. Buck explains that according to the pillar, asteroids have caused two extinctions in the past, and with the next one incoming, he believes that the only place they could find a clue to stop it is on the site of the previous ones' impact: a nearby volcano, as according to its engravings, they always fall in the same place.

However, the trio overhear their conversation, and Gavin and Gertie decide to stop them. They believe that they could easily avoid the impact due to their natural ability to fly, thus not only getting their revenge on Buck but also eradicating Earth's population and securing domination over the planet for the dinosaurs. Roger is reluctant, but Gavin and Gertie strong-arm him to cooperate. During the herd's journey to the crash site, Buck discovers that asteroids have electromagnetic properties. He theorizes that if a large number of smaller asteroids were gathered and launched into orbit, they could attract the main asteroid away from Earth.

After facing several obstacles and the interference of the dromaeosaurs, the herd arrives at Geotopia, a community of immortal animals formed inside one of the asteroids that fell long ago. There, Sid meets Brooke, a ground sloth who instantly falls in love with him. Shangri Llama, the leader of Geotopia, refuses to cooperate with Buck's plan to use the city's crystals to stop the asteroid, as they are the key to the residents' longevity. Sid inadvertently destroys the entire city when he attempts to remove one of the crystals to present Brooke with, immediately aging the Geotopians to their real ages, much to Shangri Llama's annoyance.

After Brooke convinces the other Geotopians that stopping the asteroid is more critical than their lost youth, they and the herd fill up a volcano with a gigantic ball made up of all the crystals so that the pressure launches them into space to draw the asteroid away. The dromaeosaurs attempt to intervene but soon discover they will not survive the asteroid's impact. Buck convinces them to help and tells them that the dinosaurs can live harmoniously with them. After a small meteor hits Gavin, they accidentally drop the last and biggest crystal. Still, Manny and Julian work together to throw it back into the volcano, causing Julian to earn Manny's approval. The volcano then erupts, sending the magnetic crystal shards to the sky, which sends the oncoming asteroid back into space, away from Earth.

The herd then departs for home, including Sid, who parts ways with Brooke. Still, just after they leave, a small crystal shard falls inside a hot spring, giving it rejuvenating properties and making the Geotopians and Granny, who stayed behind with them, regain their youth. After the herd returns, Manny and Ellie reconcile with Peaches, encouraging her to chase her dreams. Peaches and Julian marry afterwards, while Diego and Shira become heroes to the kids, and a rejuvenated Brooke appears during the wedding ceremony to reunite with Sid, much to his delight.