Recent from talks
Nothing was collected or created yet.
Interstate 64 in Kentucky
View on Wikipedia
I-64 highlighted in red | ||||
| Route information | ||||
| Maintained by KYTC | ||||
| Length | 191 mi[1] (307 km) | |||
| Existed | 1956–present | |||
| NHS | Entire route | |||
| Major junctions | ||||
| West end | ||||
| ||||
| East end | ||||
| Location | ||||
| Country | United States | |||
| State | Kentucky | |||
| Counties | Jefferson, Shelby, Franklin, Woodford, Scott, Fayette, Clark, Montgomery, Bath, Rowan, Carter, Boyd | |||
| Highway system | ||||
| ||||
| ||||
Interstate 64 (I-64) in the US state of Kentucky travels for 191 miles (307 km), passing by the major towns and cities of Louisville, Frankfort, Lexington, and Ashland. It has several major junctions with other Interstates, including I-65, I-71, I-264, and I-265 in Louisville and I-75 in Lexington.
The portion of I-64 in Kentucky is host to two "exceptionally significant" structures indicated by the Federal Highway Administration (FHWA). One is the Cochran Hill Tunnel,[2] a twin tube at Cherokee Park in Louisville built in 1974,[2] and the other is a 1960s-era modern-styled rest area near Winchester.[3]
In Downtown Louisville, I-64 passes under a public plaza called the Riverfront Plaza/Belvedere, one of the only structures in the state built on top of an Interstate.
Between the Indiana state line and Lexington, I-64 is named the Daniel Boone Expressway.
The entire length of I-64 in Kentucky has been designated as a portion of the Purple Heart Trail.[4][5]
Route description
[edit]This section needs expansion. You can help by adding to it. (March 2022) |

I-64 enters Kentucky at Louisville, paralleling the Ohio River along the Riverfront Expressway. It intersects with several downtown interchanges before coming to the Kennedy Interchange, where it intersects I-65 and I-71 in a tangle of ramps often referred to as the "Spaghetti Junction". Moving eastward, I-64 passes through Shelbyville, Frankfort, Midway, Lexington, Winchester, Mount Sterling, Owingsville, and Morehead, before leaving the state near Ashland at Catlettsburg. It overlaps I-75 as it makes an arc around the northeast of Lexington's urban core, with the exit numbers for I-75 used for the concurrent portion. The two Interstates separate a few miles east of downtown Lexington.
History
[edit]The Cochran Hill Tunnel in Louisville, also known as the Cherokee Park Tunnel, underwent restoration in 2001, which involved the reconstruction of the concrete pavement, the installation of new tiles, and the improvement of lighting. Later, the lights in the tunnel were replaced after multiple lights were found to be faulty. The tunnels, which opened in 1974, are one of three sites in Kentucky deemed "exceptionally significant" by the FHWA. The designation meant that it will be very difficult for the stretch of Interstate running through Cherokee Park ever to be widened.[3]
Construction began on a Kentucky Route 180 (KY 180) interchange improvement project in the summer of 2006.[6][7] The $34-million (equivalent to $48.5 million in 2024[8]) project entailed the rebuilding of six bridges, the widening of KY 180 to four lanes in the vicinity of the interchange, and the conversion of the ramps into a diamond interchange. The project was finished in the autumn of 2008.
In March 2007, Governor Ernie Fletcher signed Senate Bill 83, which allowed for an increase in speed limits on rural Interstates and parkways. Speed limits on rural sections of I-64 were increased from 65 to 70 mph (105 to 113 km/h), following an engineering study by the Kentucky Transportation Cabinet. New signage was installed in July[9]
On June 7, 2007, I-64 between the junction of I-264 and I-65 and I-71 in Downtown Louisville was closed to through traffic.[10] The section of highway featured three lanes of traffic in each direction on an elevated viaduct paralleling the Ohio River, carrying 90,000 vehicles per day. The closure was part of a $50-million (equivalent to $72.7 million in 2024[8]) refurbishment project that involved replacing 132 expansion joints and repaving more than four miles (6.4 km) of Interstate and interchanges.[11] The work was completed in two phases, starting with the entire project area being closed on three weekends in June, followed by a section of highway closed from 3rd to 22nd streets in early July to early August. However, the Interstate was not finished because of the section between Frankfort and Lexington. The state could not attain the right-of-way here because of very famous horse parks northwest of Lexington. After a couple of tries to get the right-of-way, the state was able to get the right-of-way and began construction on this segment. It was the last segment of I-64 to be completed in Kentucky.
8664
[edit]Controversially, I-64 runs through Louisville Waterfront Park, a key part of the revitalization of Downtown Louisville, and portions of the park exist under it. 8664, a grassroots campaign with popular support but little apparent political momentum, aimed to reroute and remove I-64 to enhance Louisville's waterfront. I-64 through Louisville would be resigned as I-364.[citation needed] I-64 was to be widened over the park as a part of the Ohio River Bridges Project. But plans to widen the freeway over the park were abandoned to reduce costs of the Ohio River Bridges Project.[12]
Exit list
[edit]| County | Location[13] | mi[14] | km | Exit | Destinations | Notes |
|---|---|---|---|---|---|---|
| Ohio River | 0.0 | 0.0 | Continuation into Indiana | |||
| Sherman Minton Bridge | ||||||
| Jefferson | Louisville | 0.9 | 1.4 | 1 | Western terminus and exits 0B-A on I-264 | |
| 2.7 | 4.3 | 3 | Eastern end of US 150 concurrency | |||
| 3.9 | 6.3 | 4 | ||||
| 4.5 | 7.2 | 5B | 3rd Street / River Road – Downtown | Westbound exit and eastbound entrance | ||
| 5.2 | 8.4 | 5A | Signed as exits 5A (south) and 5B (north) eastbound | |||
| 5.9 | 9.5 | 6 | Eastbound access only; I-71 exit 1B northbound to I-64 eastbound, 1A southbound to 64 westbound; southern terminus of I-71 | |||
| 6.4 | 10.3 | 7 | ||||
| 7.8 | 12.6 | 8 | Grinstead Drive | Access to Lexington Road (US 60 Alt.) to Southern and Louisville Seminaries | ||
| 8.1 | 13.0 | Cochran Hill Tunnel | ||||
| 10.3 | 16.6 | 10 | Cannons Lane | |||
| 12.3 | 19.8 | 12 | Signed as exits 12A (west) and 12B (east) eastbound; I-264 exit 19 | |||
| 14.9 | 24.0 | 15 | Signed as exits 15A (south), 15B (south-local access), and 15C (north) eastbound | |||
| Jeffersontown | 17.1 | 27.5 | 17 | Blankenbaker Parkway (KY 913) | No signage for KY 913 | |
| 18.9 | 30.4 | 19 | Signed westbound as exits 19A (south) and 19B (north); I-265 exit 25 | |||
| Shelby | Simpsonville | 27.5 | 44.3 | 28 | ||
| Shelbyville | 31.8 | 51.2 | 32 | |||
| 35.1 | 56.5 | 35 | ||||
| | 43.3 | 69.7 | 43 | |||
| Franklin | Frankfort | 47.7 | 76.8 | 48 | ||
| 48.8 | 78.5 | 49 | ||||
| 53.0 | 85.3 | 53 | Signed as exits 53A (south) and 53B (north) | |||
| 57.8 | 93.0 | 58 | ||||
| Woodford | Midway | 65.2 | 104.9 | 65 | ||
| Scott | | 68.8 | 110.7 | 69 | Ramps provide access to both eastbound and westbound US 62 | |
| Fayette | Lexington | 74.7 | 120.2 | 75 | Western terminus of concurrency with I-75, exit 118 southbound, uses I-75 exit numbers and mile markers | |
| 76.9 | 123.8 | 115 | ||||
| 79.2 | 127.5 | 113 | ||||
| 81.3 | 130.8 | 81 | Eastern end of I-75 concurrency; exit 111 northbound | |||
| 87.3 | 140.5 | 87 | ||||
| Clark | Winchester | 94.0 | 151.3 | 94 | ||
| 96.1 | 154.7 | 96 | Signed as exits 96A (south) and 96B (north) westbound | |||
| | 97.5 | 156.9 | 98 | Eastbound exit and westbound entrance; westbound exit is via a U-turn at exit 96 | ||
| | 101.6 | 163.5 | 101 | |||
| Montgomery | Mount Sterling | 109.6 | 176.4 | 110 | ||
| 112.3 | 180.7 | 113 | ||||
| Bath | Owingsville | 121.1 | 194.9 | 121 | ||
| 122.9 | 197.8 | 123 | ||||
| Rowan | | 132.8 | 213.7 | 133 | ||
| Morehead | 137.1 | 220.6 | 137 | |||
| Carter | | 156.0 | 251.1 | 156 | ||
| Olive Hill | 161.3 | 259.6 | 161 | |||
| Grayson | 171.4 | 275.8 | 172 | |||
| | 178.3 | 286.9 | 179 | |||
| Boyd | Coalton | 181.2 | 291.6 | 181 | ||
| Ashland | 185.2 | 298.1 | 185 | |||
| | 190.5 | 306.6 | 191 | |||
| | 191.0 | 307.4 | Continuation into West Virginia | |||
1.000 mi = 1.609 km; 1.000 km = 0.621 mi
| ||||||
Related route
[edit]| Location | Louisville–Glenview Manor |
|---|---|
I-264 is an inner loop route in the Louisville metropolitan area. It was created as a part of US 60 in 1949, and signed under its current designation in 1956. It is signed as the Georgia Davis Powers Shawnee Expressway between its western terminus at I-64 in Shawnee and U.S. Route 31W (US 31W)/US 60 (Dixie Highway) in Shively and as the Watterson Expressway from US 31W/US 60 to its northeastern terminus at I-71 in Glenview Manor. Along the way, it provides access to Louisville International Airport at its junction with I-65.
See also
[edit]References
[edit]- ^ Federal Highway Administration (October 31, 2002). "FHWA Route Log and Finder List: Table 1". Archived from the original on April 22, 2012. Retrieved February 24, 2009.
- ^ a b "Final List of Nationally and Exceptionally Significant Features of the Federal Interstate Highway System" (PDF). Federal Highway Administration. November 1, 2006. Archived from the original (PDF) on October 15, 2011. Retrieved September 13, 2011.
- ^ a b Elson, Martha (January 17, 2007). "Tunnel could stop wider I-64". The Courier-Journal. Louisville. Archived from the original on April 8, 2013.
- ^ "The Purple Heart Trail Program". The Military Order of the Purple Heart. Archived from the original on August 15, 2020. Retrieved March 12, 2019.
- ^ "I-64 Designated the Purple Heart Trail". KentuckyRoads.com. December 30, 2002. Archived from the original on July 16, 2019. Retrieved March 12, 2019.
- ^ Hart, Kenneth (January 1, 2007). "Road Work Ahead". The Independent. Ashland, Kentucky. Archived from the original on February 10, 2012. Retrieved January 2, 2007.
- ^ "I-64 improvement project under way in Boyd". The Independent. Ashland, Kentucky. October 5, 2007. Archived from the original on February 10, 2012. Retrieved October 10, 2007.
- ^ a b Johnston, Louis; Williamson, Samuel H. (2023). "What Was the U.S. GDP Then?". MeasuringWorth. Retrieved November 30, 2023. United States Gross Domestic Product deflator figures follow the MeasuringWorth series.
- ^ "New speed limit signs erected". The Independent. Ashland, Kentuck. January 4, 2007. Archived from the original on August 26, 2012. Retrieved January 26, 2013.
- ^ Tabor, Britney (June 8, 2007). "I-64 shutdown starts without major problems". The Courier-Journal. Vol. 139, no. 213. Louisville. p. B1. ISSN 1930-2177. Newspapers.com 181786438 (Metro edition / Zone: KY), 181787603 (Indiana edition / Zone: IN). ProQuest 241433606.
- ^ Shafer, Sheldon S. (March 11, 2007). "Big I-64 headache coming". The Courier-Journal. Vol. 139, no. 124. Louisville. p. A1. ISSN 1930-2177. Newspapers.com 181792461 (Metro edition, Zone: MT), 181786601 (Metro edition, Zone: KY), 181792092 (Indiana edition, Zone: IN). ProQuest 241403107.
- ^ "Study says cost-cutting measures could reduce Ohio River Bridges". Louisville: WDRB-TV. June 2, 2011. Archived from the original on October 6, 2014. Retrieved October 4, 2014.|
- ^ U.S. Census Bureau. "2009 Boundary and Annexation Survey Maps". Retrieved June 4, 2009.[dead link] (See also 2024 BAS Maps Archived December 26, 2024, at the Wayback Machine for Kentucky Archived December 11, 2024, at the Wayback Machine: Consolidated Cities, Counties Archived February 21, 2025, at the Wayback Machine, Incorporated Places Archived January 16, 2025, at the Wayback Machine.)
- ^ "Overview Map of Interstate 64 in Kentucky" (Map). Google Maps. Retrieved August 2, 2014.
External links
[edit]Interstate 64 in Kentucky
View on GrokipediaRoute Description
Path and Length
Interstate 64 enters Kentucky from Indiana near the Ohio River west of Louisville, spanning a total length of 191.5 miles (308.2 km) before crossing into West Virginia east of Ashland.[1][10] The route maintains a predominantly east-west alignment, facilitating connectivity between key population centers such as Louisville in Jefferson County, Frankfort in Franklin County, Lexington in Fayette County, and Morehead in Rowan County, while traversing diverse terrain from the urbanized Bluegrass Region to the more rugged eastern coalfields.[5][11] Mileage markers commence at 0 along the western border with Indiana and progress sequentially eastward to approximately mile 191 at the West Virginia line, reflecting the highway's directional flow from west to east.[1] Major junctions occur early near Louisville with I-65 (around mile 5), I-71, I-264, and I-265, transitioning to a brief 6.3-mile concurrency with I-75 near mile 104 in Lexington before continuing independently toward the eastern terminus.[5][1] This progression underscores I-64's role as a cross-state artery, bypassing densely populated areas via controlled-access alignments while integrating with local road networks at critical interchanges.[3]Major Segments and Features
Interstate 64 enters Kentucky from Indiana via the Sherman Minton Bridge, a double-deck through arch structure spanning the Ohio River into Louisville.[12] In this western segment, the highway passes through Louisville's dense urban environment, featuring elevated viaducts that parallel the Ohio River waterfront for much of its length.[13] [7] These elevated sections, constructed in the 1970s, enable the route to traverse built-up areas with high-rise buildings and industrial zones while minimizing surface-level disruptions.[7] Notable engineering elements include the Cochran Hill Tunnels, twin 500-foot-long bores excavated through local hills to avoid surface impacts in the vicinity of historic sites.[14] Transitioning eastward from Louisville, I-64 enters rural stretches south of Frankfort, winding through the gently rolling terrain of the Inner Bluegrass region.[15] This central area features undulating hills formed by Ordovician limestone and shale, with karst features such as sinkholes and fertile soils supporting extensive agriculture, including Thoroughbred horse farms and pastures.[15] The route's alignment here exploits relatively flat to moderate grades, contrasting the urban constraints to the west, though it encounters occasional steep cuts through resistant rock outcrops.[15] Further east, approaching Ashland, I-64 confronts the steeper topography of the Appalachian foothills, including the Knobs and Cumberland Escarpment physiographic provinces.[15] This segment demands substantial earthwork, with deep cuts through Pennsylvanian-age sandstones and shales and large embankment fills to maintain consistent grades amid elevation gains exceeding 1,000 feet over short distances.[15] The rugged landscape, marked by dissected plateaus and narrow valleys, highlights the engineering challenges of routing a high-speed interstate through the Eastern Kentucky Coal Field's periphery.[15]History
Planning and Initial Construction
Interstate 64 was designated as part of the national Interstate Highway System under the Federal-Aid Highway Act of 1956, which authorized approximately 41,000 miles of controlled-access highways across the United States, with the federal government covering 90 percent of construction costs.[16] In Kentucky, state planners prioritized I-64 for its potential to provide efficient east-west connectivity, linking the Louisville metropolitan area with the Appalachian coalfields in the east and facilitating the transport of coal, timber, and manufactured goods to broader markets.[6] This alignment addressed longstanding deficiencies in the state's highway network, where pre-existing routes like U.S. Route 60 were inadequate for growing freight volumes. Construction commenced in the late 1950s, with initial efforts focused on segments near Louisville and in eastern Kentucky to capitalize on federal funding allocations. Early progress included grading and paving in areas like Boyd County, where a portion opened to traffic on November 20, 1964, marking one of the first operational sections in the state.[17] Subsequent phases advanced westward and eastward progressively through the 1960s and early 1970s, overcoming topographic variations; the route's full length of approximately 191 miles across Kentucky was completed by 1976, later than most other state interstates, which were largely open by 1972.[6] The project relied on the standard 90 percent federal-to-10 percent state funding ratio established by the 1956 act, supplemented by Kentucky's contributions from fuel taxes and bonds to cover matching funds and right-of-way acquisitions. Challenges included extensive land acquisition in urban Louisville, where eminent domain proceedings displaced residents and businesses along the Ohio River corridor, and complex rural engineering in eastern Kentucky's hilly terrain, requiring bridges, cuts, and fills to maintain design standards for speed and safety.[16] These efforts aligned with national goals for defense mobility and economic efficiency, though local opposition in densely populated areas occasionally delayed approvals.Completion and Operational Milestones
The western segment of Interstate 64 from Louisville eastward to Frankfort was completed and opened to traffic by late 1967, connecting the state's largest city to its capital and facilitating early freight and commuter movement.[5] This phase linked with the existing I-65 interchange in Louisville, which had been operational since the early 1960s, establishing I-64 as a vital component of the developing national east-west corridor and enabling efficient integration with northward routes to Indiana and beyond.[5] Further extensions reached Lexington by the early 1970s, with key segments of the I-64/I-75 concurrency through the city opening incrementally starting in November 1963, allowing for multiplexed travel that bolstered regional connectivity between central Kentucky's urban centers.[18] By 1972, these connections solidified I-64's role in linking I-75's north-south axis, promoting industrial expansion in Fayette County through improved access to manufacturing hubs and markets.[1] The eastern terminus advanced progressively, with the Boyd County section opening on November 20, 1964, to support Appalachian traffic flows.[17] Full completion of I-64 across Kentucky, extending to the West Virginia state line, occurred in December 1976, marking the route's operational maturity and enabling seamless interstate continuity for over 190 miles.[1] This endpoint integration enhanced national corridor status, driving economic linkages to coal and steel industries in eastern Kentucky and beyond.[1] In the ensuing decade, initial capacity upgrades addressed rising volumes, including lane additions in high-traffic zones near Louisville and Lexington during the 1980s to mitigate congestion and improve safety amid growing commercial use.[5]The 8664 Campaign and Waterfront Developments
The 8664 campaign, co-founded in 2005 by Louisville businessmen Tyler Allen and J.C. Stites, advocated for the demolition of the elevated Riverside Expressway segment of Interstate 64 in downtown Louisville and its replacement with a four-lane surface parkway integrated into an expanded waterfront park system.[13] Proponents argued that this reconfiguration would reclaim severed urban land along the Ohio River, foster pedestrian-oriented revitalization akin to freeway removals in cities like San Francisco, and avoid worsening congestion through mechanisms such as induced demand, where added road capacity purportedly generates equivalent new traffic.[7] The initiative gained traction among local urbanists critiquing mid-20th-century highway construction's disruption of neighborhoods but faced skepticism over its feasibility for handling substantial freight and commuter volumes on a downgraded alignment. The effort directly conflicted with the Ohio River Bridges Project, a long-planned initiative formalized in the 1990s and executed from 2013 to 2016 by the Kentucky Transportation Cabinet and Indiana Department of Transportation, which constructed the Abraham Lincoln Bridge as a new I-65 Ohio River crossing and reconfigured the Kennedy Interchange—known as Spaghetti Junction—to streamline I-64 flows.[19] Despite 8664's assertions of environmental degradation, fiscal waste, and self-fulfilling traffic growth, the $2.3 billion project proceeded, incorporating I-64 widening and ramp improvements to address chronic bottlenecks serving over 120,000 average annual daily vehicles in the corridor.[20] Ultimately, the campaign failed to alter project outcomes, as assessments underscored the necessity of interstate-grade capacity to sustain regional commerce reliant on efficient truck throughput and avoid diverting volumes to parallel arterials ill-equipped for interstate speeds or volumes. Post-completion analyses, including 2018 traffic data compared to pre-construction baselines, indicated enhanced interchange operations and moderated peak delays, validating the prioritization of engineered throughput over boulevard reclamation amid persistent demand exceeding 100,000 vehicles daily.[21] Louisville's waterfront developments proceeded independently through parks and trails, but without the proposed highway depression, preserving the corridor's role in mitigating broader network strain.Improvements and Maintenance
Key Rehabilitation Projects
In the mid-1980s, the Kentucky Transportation Cabinet implemented a statewide program to rehabilitate concrete pavements on interstates, including sections of I-64, by breaking, seating, and overlaying approximately 750 lane-miles of deteriorated Portland cement concrete (PCC) surfaces with asphalt to restore ride quality and extend service life amid increasing traffic volumes.[22] This approach addressed cracking and faulting common in older interstate pavements constructed in the 1960s and 1970s, prioritizing structural integrity over full reconstruction.[22] A major effort in 2007 targeted the I-64 Riverside viaduct in Louisville, spanning from Preston Street westward to the I-264 interchange and paralleling the Ohio River, where rehabilitation work focused on repairing corrosion-damaged elements and enhancing seismic resilience in the elevated structure carrying high daily volumes.[23] The $50 million project involved structural reinforcements and deck preservation to mitigate risks from aging steel and concrete exposed to deicing salts and environmental factors.[1] In central Kentucky, pavement resurfacing and shoulder widening projects during the 1990s and early 2000s responded to escalating truck traffic from regional manufacturing, with resurfacing overlays applied to segments between Frankfort and Shelbyville to improve skid resistance and add safety buffers against edge drop-offs.[24] These upgrades, informed by KYTC's interstate restoration policies, emphasized maintenance of load-bearing capacity without lane additions.[25]Recent Expansions and Upgrades
In Shelby County, a $118 million widening and improvement project on Interstate 64, spanning 11 miles between the KY 395 interchange near Louisville and the KY 53 interchange near Lexington, began in February 2025 and is scheduled for completion in fall 2027.[9][26] The initiative includes adding lanes for increased capacity, pavement rehabilitation, and full reconstruction of the KY 53 interchange to address growing congestion from regional traffic volumes exceeding design standards in this corridor.[27] In Franklin County, a $10.5 million milling and paving project on I-64 between mile markers 53 and 58, encompassing the Frankfort exits, commenced in August 2025 with an expected completion by fall 2026.[28] Awarded to HG Mays Corporation, the work involves removing existing asphalt, repaving, and enhancements to extend pavement life and improve ride quality amid rising maintenance demands from heavy freight and commuter use.[29] The I-Move Kentucky program, a $180 million effort initiated around 2020, has reconstructed the I-64/I-265 interchange near Louisville using a partial turbine design with braided ramps and flyover elements to reduce weaving and enhance capacity, achieving substantial completion by November 2024.[30][31] Complementary studies under this initiative evaluate new connector options near Eastwood and Fisherville to further mitigate bottlenecks by distributing traffic flows from I-64 into eastern Jefferson County suburbs.[32][33]Exit List
| Exit | Destinations | Notes |
|---|---|---|
| – | I-64 west / US 150 west | Continuation into Indiana across Sherman Minton Bridge over Ohio River at mile 0.0 |
| 1 | I-264 east – KY 841 (Gene Snyder Freeway), New Albany IN | Major junction; partial cloverleaf interchange |
| 3 | US 150 east / 22nd Street | Serves western Louisville |
| 4 | 9th Street / Roy Wilkins Avenue | Access to downtown Louisville |
| 5 | I-65 south – Elizabethtown, I-71 north – Cincinnati, US 31W / US 150 – Downtown Louisville, University of Louisville | Kennedy Interchange; major junction with I-65 and I-71 |
| 7 | Story Avenue / Mellwood Avenue | Serves Butchertown and Portland neighborhoods |
| 8 | Grinstead Drive | Local access in Louisville |
| 10 | Cannons Lane | Serves Cherokee Triangle area |
| 12 | I-264 west – Louisville International Airport, Fort Knox | Access to southern Louisville; partial interchange (MM 12.0) |
| 15A | Hurstbourne Parkway north – Jeffersontown | Split lanes eastbound |
| 15B | Hurstbourne Parkway south – Middletown | Split lanes eastbound |
| 17 | North Blankenbaker Parkway | Serves eastern Jefferson County |
| 20 | US 60 – Prospect, Jeffersontown | Split ramps eastbound |
| 28 | KY 1848 – Simpsonville | Welcome center eastbound |
| 32 | KY 55 – Taylorsville, Shelbyville | High-volume interchange |
| 35 | KY 53 – Shelbyville | Weigh station westbound nearby |
| 43 | KY 395 – Waddy, Peytona | Local rural access |
| 48 | KY 151 south / US 127 south – Lawrenceburg, Graefenburg | Serves Anderson County |
| 53A | US 127 south – Lawrenceburg Road, Lawrenceburg | Split ramps eastbound |
| 53B | US 127 north – Frankfort | Split ramps eastbound; access to state capital |
| 58 | US 60 east / Versailles Road – Versailles, Frankfort | Serves Franklin County |
| 65 | KY 341 / US 62 west – Midway, Versailles | Rest area westbound |
| 69 | US 62 east – Georgetown | Last exit before I-75 concurrency |
| 75 | I-75 north – Georgetown, Cincinnati | Western terminus of I-64/I-75 concurrency (mile 74.7); subsequent exits use I-75 numbering and mile markers until split east of Lexington |
| 87 | KY 859 – Bluegrass Station | During concurrency; signed as I-75 Exit 104 |
| 94 | KY 1958 / Van Meter Road / KY 627 – Winchester | During/near end of concurrency |
| 96 | KY 627 – Winchester, Paris | |
| 98 | Mountain Parkway east – Salyersville, Jenkins | Spur route; MM 98.0 |
| 101 | US 60 west – Winchester | Rest area eastbound |
| 110 | US 460 / KY 11 – Flemingsburg, Mt. Sterling | |
| 113 | US 60 – Mt. Sterling | |
| 115 | KY 922 – Airport, Lexington | During concurrency; signed as I-75 Exit 115; Blue Grass Airport |
| 121 | KY 36 – Frenchburg, Owingsville | |
| 123 | US 60 – Owingsville | |
| 133 | KY 801 – Morehead | |
| 137 | KY 32 – Morehead, Flemingsburg | Rest area eastbound |
| 156 | KY 2 / KY 59 – Olive Hill, Vanceburg | |
| 161 | US 60 – Olive Hill | |
| 172 | KY 1 / KY 7 / KY 9 (AA Highway) – Grayson, Maysville | Rest area westbound |
| 179 | KY 67 (Industrial Parkway) – Wurtland, Greenup | Access to industrial areas |
| 181 | US 60 – Grayson | |
| 185 | KY 180 / US 60 – Cannonsburg, Ashland | Serves Ashland area |
| 191 | US 23 – Ashland, Louisa | Eastern terminus in Kentucky; continues into West Virginia |
