Ivan Vladimirovich Lopukhin (Russian: Ива́н Влади́мирович Лопухи́н; 6 March [O.S. 24 February] 1756 – 4 July [O.S. 22 June] 1816) was a Russian philosopher, mystic, writer and humanitarian.

Ivan Lopukhin was born to the wealthy Lopukhin family in 1756 in Voskreskenskoye, Oryol Governorate, Russia.

Lopukhin joined the Preobrazhensky Lifeguard regiment in 1775. He retired a colonel 7 years later due to health concerns.

After serving as a counselor and later court president on the Moscow Criminal court between 1782 and 1785, he was introduced to rosicrucianism, martinism and freemasonry through his friend Nikolay Novikov and began a career as a writer and printer, while entering civil service. He became Senator in 1798.

In 1801, Tsar Alexander I asked Lopukhin to investigate complaints by the Dukhobortsy, his reports in 1802 leading to their resettlement on the Molochnaya River, along with other religious heretics (sektanty), mostly Molokane.