From the beginning of her career, Santiago prioritized creating games that evoke emotions and connect with players on a deeper level. This philosophy is evident in the design of "Flow", "Flower", and "Journey", which all prioritize emotional impact over traditional gameplay mechanics.

Santiago has consistently championed artistic expression in game development, believing that games can be a powerful medium for conveying complex ideas and emotions. Her work reflects a commitment to pushing the boundaries of what games can be and showcasing the artistic potential of the medium.

Through her roles at PlayStation and Annapurna Interactive, Santiago has actively supported independent game developers, providing them with resources and platforms to bring their unique visions to life. She believes that independent developers are essential for driving innovation and creativity in the industry.