Keye Luke (Chinese: 陸錫麒; pinyin: Lù Xīqí; Jyutping: Luk6 Sek3 Kei4; June 18, 1904 – January 12, 1991) was a Chinese-born American actor, and a founding member of the Screen Actors Guild. He portrayed Lee Chan, the "Number One Son" in the Charlie Chan films, the original Kato in the 1939–1941 Green Hornet film serials, Brak in the 1960s Space Ghost cartoons, Master Po in the television series Kung Fu, and Mr. Wing in the Gremlins films. He was the first Chinese-American contract player signed by RKO, Universal Pictures, 20th Century-Fox and Metro-Goldwyn-Mayer and was one of the most prominent Asian actors of American cinema in the mid-20th century.

Luke's father, Lee Luke, was born in San Francisco in 1880, and traveled to China several times where he married Keye's mother, Down Cook. Lee Luke established an art/import shop in Seattle Chinatown.

Born in Canton (Guangzhou), China, during the Qing dynasty, Luke was raised in Seattle. He had four siblings who all moved from Seattle to California during the Great Depression. His younger brother Edwin Luke also became an actor in the Charlie Chan series. The Luke family includes Washington assistant attorney-general Wing Luke.^{[citation needed]}

In Seattle, Luke attended Franklin High School, where he contributed cartoons and illustrations to school publications. He became a naturalized citizen of the United States in 1944.

Before becoming an actor, he was an artist in Seattle and, later, Hollywood. Luke worked on several of the murals inside Grauman's Chinese Theatre. He did some of the original artwork for the pressbook of the original King Kong (1933). Luke also painted a mural for the casino set in The Shanghai Gesture (1941).

He published a limited edition set of pen and ink drawings of the Rubaiyat of Omar Khayyam in the 1950s. He also created illustrations for the books The Unfinished Song of Achmed Mohammed by Earle Liederman, Blessed Mother Goose by Frank Scully and an edition of Messer Marco Polo by Brian Oswald Donn-Byrne (unpublished). Other artwork completed by Luke included the dust jackets for books published in the 1950s and 1960s. It was through his studio art work that he was recruited for his earliest movie roles.

Luke made his film debut for Metro-Goldwyn-Mayer in The Painted Veil (1934), and played his first major role, as Charlie Chan's eldest son, Lee Chan (called "Number One Son" by his father) in Charlie Chan in Paris (1935). He became a regular in the series, where Lee Chan alternately helped and distracted his father in each of his murder cases. Lee Chan is culturally American and was an Olympic Gold Medalist in 100-metre swimming in Charlie Chan at the Olympics (1937). Luke appeared seven times as Lee Chan opposite Warner Oland's Charlie Chan. He left the Charlie Chan series in 1938, shortly after Oland died. The unfinished Oland-Luke film Charlie Chan at the Ringside was completed as Mr. Moto's Gamble (1938), with Luke now opposite Peter Lorre.

Luke worked prolifically with several Hollywood studios. Metro-Goldwyn-Mayer cast him in a recurring role in its Dr. Kildare film series, and Monogram Pictures featured him in its Frankie Darro comedies and starred him as Mr. Wong in Phantom of Chinatown. Unlike Boris Karloff, who preceded him in the Mr. Wong role, Luke played the detective without any exotic touches. His Mr. Wong, of Chinese descent and able to speak Chinese, was otherwise an ordinary American detective with no trace of a foreign accent.