Lesidren Island (Bulgarian: остров Лесидрен, romanized: ostrov Lesidren, IPA: [ˈɔstrof ˈlɛsidrɛn]) is the second largest and southernmost island in the Zed group off the north coast of Varna Peninsula, Livingston Island in the South Shetland Islands, Antarctica. The island is ice-free, extending 800 by 600 m (870 by 660 yd) with surface area 33 hectares (82 acres). Separated from the neighbouring Phanagoria Island and Koshava Island by channels 130 and 140 m (140 and 150 yd) wide respectively. The area was visited by early 19th century sealers.

The island is named after the settlement of Lesidren in northern Bulgaria.

Lesidren Island is located at 62°26′10″S 60°08′55″W / 62.43611°S 60.14861°W / -62.43611; -60.14861 which is 1.53 km (0.95 mi) north of Williams Point on Livingston Island. British mapping in 1968, Chilean in 1971, Argentine in 1980, Bulgarian in 2005 and 2009.

This article includes information from the Antarctic Place-names Commission of Bulgaria which is used with permission.