Lulu Spencer is a fictional character from General Hospital, an American soap opera on the ABC network, portrayed by Alexa Havins Bruening. Previously, Lulu was portrayed by child actress, Tessa Allen from 2004 to 2005. The role was most notably portrayed by Julie Marie Berman from 2005 to 2013. Emme Rylan stepped into the role in 2013 and exited in 2020. Havins Bruening assumed the role in 2024.

Originally introduced in 1994, under executive producer, Wendy Riche, and created by head writer Claire Labine, Lulu is the only daughter of Supercouple, Luke and Laura Spencer. Sent away for her own protection as a child, the character is rapidly aged into a teenager in 2005 with Julie Marie Berman in the role. Lulu, much like her mother garners the attention of every young man in town from her stepbrother, Dillon Quartermaine, to the nerdy Damian Spinelli. From 2006 to 2009, Lulu is embroiled in a love triangle with Logan Hayes, the son of her father's nemesis Scott Baldwin, and mob prince, Johnny Zacchara. Much of Lulu's life mirrors that of her mother's, as she also faces mental instability resulting from the accidental murder of a loved one, in Lulu's case, her ex-boyfriend, Logan.

In addition to her early romances, Lulu is also known for the show's first onscreen abortion as well her supercouple pairing with Dante Falconeri, and her rivalry turned friendship with Maxie Jones. Berman earned two Daytime Emmy Awards in the Outstanding Younger Actress in a Drama Series category for her portrayal of Lulu in 2009 and 2010, and a third for Outstanding Supporting Actress in a Drama Series in 2013.

Since her on-screen birth, Lulu was portrayed by several child actors; first by Amanda and Kerrianne Harrington from 1994 to 1995, then Clare and Maribel Moses, from March 1995 to September 1995, next by Alysin and Kelli Griffith from 1995 to 2001, followed by Stephanie Allen from September 11, 2001 to December 23, 2003. Child actress, Tessa Allen stepped into the role on April 19, 2004, and last appeared on June 17, 2005.

Julie Marie Berman joined the cast of General Hospital in the fall of 2005 as a SORASed Lulu, making her first appearance on October 28, 2005. The casting immediately garnered much attention due to Berman's strong resemblance to Genie Francis who played Laura; Lulu and Laura's strong resemblance was often mentioned within the series. In July 2012, Berman informed producers that she had no plans of renewing her contract when it expired in November. Despite no official word from ABC or Berman, rumors began to circulate that Berman was about to vacate the role. After months of speculation, on February 26, 2013, an issue of Soaps In Depth confirmed that Berman was indeed leaving the series and had just filmed her final scenes.

On March 6, 2013, TV Guide's Michael Logan hinted on Twitter that an actor from General Hospital would be joining the cast of The Young and the Restless while a Y&R alum would be coming to GH. Meanwhile, Jamey Giddens of Daytime Confidential reported that several sources said Emme Rylan, formerly known for her role on Guiding Light as Lizzie Spaulding and The Young and the Restless as Abby Newman, had been cast as Lulu, but nothing was official at the time. Several sources including Soap Opera Digest later confirmed that the reports were indeed true. Berman made her last appearance on March 22, 2013. Rylan took to Twitter and confirmed her first air date at April 11. In February 2019, Rylan announced she had renewed her deal with the soap to continue her portrayal of Lulu. On December 1, 2020, after increased speculation, Rylan exited the role.

On August 5, 2024, TV Insider reported a casting call for the role of "Lauren," suggesting the details of "Lauren" sounded much-like the role of Lulu. The following day, Rylan verified the reports of the recast and expressed her disappointment in the decision, stating: "Although I am very disappointed with their choice, I am glad to finally have closure." On September 10, 2024, Daytime Confidential reported Alexa Havins Bruening was cast in the role; according to their report, Jennifer Landon and Marci Miller were also in-talks to being cast. She made her episodic debut during the final moments of the November 19, 2024, episode.

Lesley Lu Spencer is born on August 8, 1994, in Port Charles, New York to Luke and Laura Spencer. The character is named for her maternal grandmother, Lesley and the alias "Lulu" used by her mother when her parents are on the run from mob boss, Frank Smith. Laura asks her close friend, Tiffany Hill to be Lulu's godmother. Because of Luke's association with mob boss Sonny Corinthos, Lulu's infancy is plagued by danger, with her mother fleeing town with her at one point. As an infant, Lulu is diagnosed with aplastic anemia, forcing Laura to reveal the existence of another son, Nikolas Cassadine, born during her captivity with Stavros Cassadine. Nikolas saves Lulu's life with a bone marrow transplant, but Luke and Laura's marriage is destroyed by the revelation of this secret. After the divorce, Lulu is primarily raised by her mother, but Luke and Laura eventually reconcile and plan to remarry. When Laura appears to have murdered her stepfather, Rick Webber, she becomes catatonic and Lulu is sent to be raised by Lesley and makes small appearances between 2003 and early 2005. In November 2005, the character is aged to 17 re-establishing her birth year as 1988.