Meroë (/ˈmɛroʊiː/; also spelled Meroe; Meroitic: 𐦨𐦡𐦷𐦡𐦥𐦢, romanized: Medewi; Arabic: مرواه, romanized: Meruwah and مروي, Meruwi; Ancient Greek: Μερόη, romanized: Meróē) was an ancient city on the east bank of the Nile about 6 km north-east of the Kabushiya station near Shendi, Sudan, approximately 200 km north-east of Khartoum. Near the site is a group of villages called Bagrawiyah (Arabic: البجراوية). This city was the capital of the Kingdom of Kush for several centuries from around 590 BC, until its collapse in the 4th century AD. The Kushitic Kingdom of Meroë gave its name to the "Island of Meroë", which was the modern region of Butana, a region bounded by the Nile (from the Atbarah River to Khartoum), the Atbarah and the Blue Nile.

The city of Meroë was on the edge of Butana. There were two other Meroitic cities in Butana: Musawwarat es-Sufra and Naqa. The first of these sites was given the name Meroë by the Persian king Cambyses, in honor of his sister who was called by that name. The city had originally borne the ancient appellation Saba, named after the country's original founder. The eponym Saba, or Seba, is named for one of the sons of Cush (see Genesis 10:7). The presence of numerous Meroitic sites within the western Butana region and on the border of Butana proper is significant to the settlement of the core of the developed region. The orientation of these settlements exhibit the exercise of state power over subsistence production.

The Kingdom of Kush which housed the city of Meroë represents one of a series of early states located within the middle Nile. It was one of the earliest and most advanced states found on the African continent. Looking at the specificity of the surrounding early states within the middle Nile, one's understanding of Meroë in combination with the historical developments of other historic states may be enhanced through looking at the development of power relation characteristics within other Nile Valley states.

The site of the city of Meroë is marked by more than two hundred pyramids in three groups, of which many are in ruins. They have the distinctive size and proportions of Nubian pyramids.

Meroë was the southern capital of the Kingdom of Kush. The Kingdom of Kush spanned the period c. 800 BC – c. 350 AD. Initially, its main capital was farther north at Napata. King Aspelta moved the capital to Meroë, considerably farther south than Napata, possibly c. 591 BC, just after the sack of Napata by Egyptian Pharaoh Psamtik II.

Martin Meredith states the Kushite rulers chose Meroë, between the Fifth and Sixth Cataracts, because it was on the fringe of the summer rainfall belt, and the area was rich in iron ore and hardwood for iron working. The location also afforded access to trade routes to the Red Sea. The city of Meroë was located along the middle Nile which is of much importance due to the annual flooding of the Nile river valley and the connection to many major river systems such as the Niger which aided with the production of pottery and iron characteristic to the Meroitic kingdom that allowed for the rise in power of its people. According to partially deciphered Meroitic texts, Meroitic "d" was transcribed in foreign languages as "r", with the native name of the city being Medewi.

The Kings ruled over Napata and Meroë. The seat of government and the royal palace were in Meroë. The Main temple of Amun was located in Napata. Kings and many queens are buried in Nuri, some queens are buried in Meroë, in the West Cemetery. The earliest king was Analmaye (542–538 BC) and the last king of the first phase is Nastasen (335–315 BC)

In the fifth century BC, Greek historian Herodotus described it as "a great city...said to be the mother city of the other Ethiopians."