The Minimal Supersymmetric Standard Model (MSSM) is an extension to the Standard Model that realizes supersymmetry. MSSM is the minimal supersymmetrical model as it considers only "the [minimum] number of new particle states and new interactions consistent with "Reality". Supersymmetry pairs bosons with fermions, so every Standard Model particle has a (yet undiscovered) superpartner. If discovered, such superparticles could be candidates for dark matter, and could provide evidence for grand unification or the viability of string theory. The failure to find evidence for MSSM using the Large Hadron Collider has strengthened an inclination to abandon it.

The MSSM was originally proposed in 1981 to stabilize the weak scale, solving the hierarchy problem. The Higgs boson mass of the Standard Model is unstable to quantum corrections and the theory predicts that weak scale should be much weaker than what is observed to be. In the MSSM, the Higgs boson has a fermionic superpartner, the Higgsino, that has the same mass as it would if supersymmetry were an exact symmetry. Because fermion masses are radiatively stable, the Higgs mass inherits this stability. However, in MSSM there is a need for more than one Higgs field, as described below.

The only unambiguous way to claim discovery of supersymmetry is to produce superparticles in the laboratory. Because superparticles are expected to be 100 to 1000 times heavier than the proton, it requires a huge amount of energy to make these particles that can only be achieved at particle accelerators. The Tevatron was actively looking for evidence of the production of supersymmetric particles before it was shut down on 30 September 2011. Most physicists believe that supersymmetry must be discovered at the LHC if it is responsible for stabilizing the weak scale. There are five classes of particle that superpartners of the Standard Model fall into: squarks, gluinos, charginos, neutralinos, and sleptons. These superparticles have their interactions and subsequent decays described by the MSSM and each has characteristic signatures.

The MSSM imposes R-parity to explain the stability of the proton. It adds supersymmetry breaking by introducing explicit soft supersymmetry breaking operators into the Lagrangian that is communicated to it by some unknown (and unspecified) dynamics. This means that there are 120 new parameters in the MSSM. Most of these parameters lead to unacceptable phenomenology such as large flavor changing neutral currents or large electric dipole moments for the neutron and electron. To avoid these problems, the MSSM takes all of the soft supersymmetry breaking to be diagonal in flavor space and for all of the new CP violating phases to vanish.

There are three principal motivations for the MSSM over other theoretical extensions of the Standard Model, namely:

These motivations come out without much effort and they are the primary reasons why the MSSM is the leading candidate for a new theory to be discovered at collider experiments such as the Tevatron or the LHC.

The original motivation for proposing the MSSM was to stabilize the Higgs mass to radiative corrections that are quadratically divergent in the Standard Model (the hierarchy problem). In supersymmetric models, scalars are related to fermions and have the same mass. Since fermion masses are logarithmically divergent, scalar masses inherit the same radiative stability. The Higgs vacuum expectation value (VEV) is related to the negative scalar mass in the Lagrangian. In order for the radiative corrections to the Higgs mass to not be dramatically larger than the actual value, the mass of the superpartners of the Standard Model should not be significantly heavier than the Higgs VEV – roughly 100 GeV. In 2012, the Higgs particle was discovered at the LHC, and its mass was found to be 125–126 GeV.

If the superpartners of the Standard Model are near the TeV scale, then measured gauge couplings of the three gauge groups unify at high energies. The beta-functions for the MSSM gauge couplings are given by