Misrata (/mɪsˈrɑːtə/ miss-RAH-tə; Arabic: مصراتة, romanized: Miṣrāta, Libyan Arabic: Məṣrāta; also spelled Misratah and known by the Italian spelling Misurata) is a city in northwestern Libya located in the Misrata District, situated 187 km (116 mi) to the east of Tripoli on the Mediterranean coast near Cape Misrata. With a population of about 881,000, it is the third-largest city in Libya, after Tripoli and Benghazi. It is the capital city of the Misrata District and has been called the economic and trade capital of Libya. Its harbor is at Qasr Ahmad.

The name "Misrata ⵎⵙⵔⴰⵜⴰ" derives from the Misrata tribe, a section of the larger Berber Hawwara confederacy, whose homeland in Antiquity and the early Islamic period was coastal Tripolitania.

"Trirone Acrone", the oldest description mentioned by Ptolemy III Euergetes of Misrata because it consists of three heads of land stretching into the sea depth, and got Misrata importance by being at the crossroads of many convoys and also because it is in the middle of an agricultural area with the name of "Cephalae Promentorium" (Kevalay) of the Greek geographer Strabo. And the city of Misrata is one of the commercial stations that have been built by the Phoenicians, since more than 3000 years (The Tenth Century BC) to the north-western parts of the Libyan coast. The flag then by the name of Thubactis Misrata and know that name in relation to the Berber tribe of Misurata (The Misurateens), which means the sailors.^{[citation needed]}

Modern Misrata was established around the 7th century AD during the beginning of modern Libya's rule by the Caliphate. Some contemporary sources claim the town existed prior to Islamic rule,^[which?] during the Roman Empire era and that its initial Arabic name derived from its Roman name Thubactis. David Mattingly, author of Tripolitania, a comprehensive reference book on northwestern Libya, stated that identification of Misrata as the ancient Thubactis is particularly problematic, complicated and "defies an easy answer." Nonetheless, the Roman town was located at some point on the oasis upon which the modern city sits. The two common identifications are at the eastern and western anchorages of modern Misrata or south and inland of the city, respectively. The Roman town was recorded as one of the six municipia (small self-governing cities) of the Tripolitania province, a rank below coloniae (cities with full citizenship rights.)

In any case, in the 7th century, Misrata served as a caravan supply center and an important port. Merchant traders from Misrata were well known throughout the Sahara during the years of the Caliphate (7th–19th centuries). In addition to its strategic location, the city established itself as one of Libya's oldest producers of luxury carpets. The Misrata tribe, a section of the larger Berber Hawwara confederacy, inhabited the coastal region of Tripolitania during the Roman and early Arab eras.

The region of Tripolitania, which included Misrata, came under the regency of the Ottoman Empire in 1551. By the beginning of the 19th century, Misrata had established itself as a major center for the Trans-Saharan trade route, where caravans carrying gold, leather, and slaves regularly stopped. Because of the rainfall along the coast, which was abundant compared to other cities in Tripolitania, and supplemental water from underground springs, Misrata's inhabitants were able to engage in unusually fertile agriculture in this largely arid region. The city was filled with thick areas of vegetable gardens while the surrounding countryside included fields of wheat, barley, date palms and olive orchards. Misrata's artisans also expanded on the city's ancient carpet industry for which it was regionally renowned. Although Misrata contained a well-built harbor, most of its long-distance trade was overland because the city of Benghazi to the east served as the preferable substitute for maritime shipping.

As a result of the abolition of slavery and increasing European colonial influence in Sub-Saharan Africa, Trans-Saharan trade declined and consequently Misrata's role in the trade decreased. However, the decline in Trans-Saharan trade saw the establishment of weekly and permanent markets in the city, replacing the seasonal markets associated with long-distance trade. Because of this new economic situation, the residents of the countryside devoted less time to pastoralism, husbandry and guide service for foreign traders and began to shift their focus on agricultural production. Farmers concentrated on growing cash crops, relying on market relations to provide income for their families, instead of subsistence farming and periodic barter exchanging. Bedouins increasingly abandoned their nomadic lifestyle and began to settle into permanent dwellings within the city limits. To cope with an rising population due to immigration from the surrounding areas, Misrata witnessed a construction boom in the late 19th century. A covered produce market and numerous streets lined with shops were built in addition to new district and municipal government offices, a renovated Ottoman army barracks and several Turkish-style houses for the city's wealthy families.

Two clans, the Muntasir and Adgham, dominated the political, social and economic aspects of Misrata and led the local tribes against their Turkish overlords during various periods of tension. There were many wealthy families in the city, but the Muntasirs, who were of Arabian descent, and the Adghams, who descended from Ottoman officers who settled in the province in previous centuries, were the most prominent. They made their income from commerce and protected their wealth by cooperating with the Ottoman provincial authorities. Both had extended families and economic holdings not just in Misrata, but also the provincial capital of Tripoli as well as the eastern Cyrenican towns of Benghazi and Derna. The Aghdams had traditionally resisted efforts by the central Ottoman government in Istanbul to reestablish direct control over Tripoli Province and, under the leadership of Osman al-Aghdam, they led a rebellion against the Ottomans and their local allies in 1835. After their eventual defeat in 1858, they were left in an inferior position to that of the Muntasirs. The Aghdams remained a powerful force nonetheless and their competition with the Muntasirs for leading positions within the local and regional government dominated Misratan politics. Misrata's urban residents did not contribute much to the political scene and avoided contact with the Ottoman authorities out of concern of conscription into the army and provincial tax collection. In contrast, the rural areas of Misrata were populated mostly by fellahin (peasantry) and former Bedouins who had retained their tribal affiliations and loyalties and thus involved themselves in competition for political influence.