Driven by the need to maintain Nora's cryogenic stasis and find a cure for her condition, Mr. Freeze resorts to criminal activities. He targets laboratories, banks, and businesses to steal money, equipment, and resources necessary for his research.

Mr. Freeze's criminal activities inevitably bring him into conflict with Batman. Their encounters are often characterized by strategic battles involving Freeze's cryogenic weaponry and Batman's detective skills and technological countermeasures. Batman represents both an obstacle to Freeze's goals and a reminder of the humanity he has lost.

Mr. Freeze views his criminal actions as a necessary evil to save Nora's life. He often justifies his behavior by claiming that his love for Nora outweighs the suffering he inflicts on others. This moral ambiguity complicates his character and challenges Batman's perception of him.

Throughout his criminal career, Mr. Freeze continuously refines and improves his cryogenic technology. He develops increasingly powerful and sophisticated weapons, devices, and strategies to evade capture and achieve his goals. His scientific expertise makes him a formidable adversary.