Paleopathology
Paleopathology
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Paleopathology

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Paleopathology

Paleopathology, also spelled palaeopathology, is the study of ancient diseases and injuries in organisms through the examination of fossils, mummified tissue, skeletal remains, and analysis of coprolites. Specific sources in the study of ancient human diseases may include early documents, illustrations from early books, painting and sculpture from the past. All these objects provide information on the evolution of diseases as well as how past civilizations treated conditions. Studies have historically focused on humans, although there is no evidence that humans are more prone to pathologies than any other animal.

The word paleopathology is derived from the Ancient Greek roots of palaios (παλαιός) meaning "old", pathos (πάθος) meaning "experience" or "suffering", and -logia (-λογία), "study".[page needed]

Paleopathology is an interdisciplinary science, meaning it involves knowledge from many sectors including (but not limited to) "clinical pathology, human osteology, epidemiology, social anthropology, and archaeology". It is unlikely that one person can be fluent in all necessary sciences. Therefore, those trained in each are important and make up a collective study. Training in anthropology and archaeology is arguably most important, because the analysis of human remains and ancient artifacts are paramount to the discovery of early disease.

Historical evidence shows that deviations from good health have long been an interest to humans. Although the content that makes up this study can be traced through ancient texts, the term "paleopathology" did not have much traction until the 20th century. This time period saw an increase in case studies and "published reports on ancient diseases". Ancient texts that are thousands of years old record instances of diseases such as leprosy.

From the Renaissance to the mid-nineteenth century, there was increasing reference to ancient disease, initially within prehistoric animals although later the importance of studying the antiquity of human disease began to be emphasized. Some historians and anthropologists theorize that "Johann Friederich Esper, a German naturalist...heralds the birth of paleopathology." Although it wasn't until between the mid nineteenth century and World War I that the field of human paleopathology is generally considered to have come about. During this period, a number of pioneering physicians and anthropologists, such as Marc Armand Ruffer, G. Elliot Smith, Frederic Wood Jones, Douglas E. Derry, and Samuel George Shattock, clarified the medical nature of ancient skeletal pathologies. This work was consolidated between the world wars with methods such as radiology, histology and serology being applied more frequently, improving diagnosis and accuracy with the introduction of statistical analysis. It was at this point that paleopathology can truly be considered to have become a scientific discipline. Today, the use of biomedical technology like DNA and isotopic analysis are major developments for pathological knowledge.

After World War II paleopathology began to be viewed in a different way: as an important tool for the understanding of past populations, and it was at this stage that the discipline began to be related to epidemiology and demography.

New techniques in molecular biology also began to add new information to what was already known about ancient disease, as it became possible to retrieve DNA from samples that were centuries or millennia old.

To analyze human remains of the past, different techniques are used depending on the type of remains that are found. For example, "the approach to palaeopathological samples depends on the nature of the sample itself (e.g. bone, soft tissue or hair), its size (from minimal fragments to full bodies), the degree of preservation and, very importantly, the manipulation allowed (from intact sample ready for display to absolute access and freedom to undertake any kind of valuable destructive analysis including a full autopsy study)." Much research done by archaeologists and paleopathologists is on bones. The basic nature of bones allows them to not degrade over time like other human remains would, making osteopathology important in studying ancient disease. Human osteopathology is classified into several general groups:

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