The Panche or Tolima are an indigenous group of people that lived in what is now Colombia. They inhabited the southwestern parts of the department of Cundinamarca and the northeastern areas of the department of Tolima, close to the Magdalena River. At the time of the Spanish conquest, more than 30,000 Panche were living in what would become the New Kingdom of Granada. Early knowledge about the Panche has been compiled by scholar Pedro Simón.

The Panche were inhabiting the lower altitude southwestern areas of the Cundinamarca department, close to the Magdalena River. Their northern neighbours were the Muzo in the northeast and the Pantágora in the northwest, in the east the Muisca, in the southeast the Sutagao and to the south and southwest the Pijao. The northern limits were defined by the Río Negro and the Guarinó River and the southern limits the Coello and Fusagasugá Rivers.

The Panche people were organized in a loose confederation with different subgroups whose names still remain as municipalities of Cundinamarca.

The Panche were a strong group of warriors who fought numerous battles with the neighbouring Muisca. They walked partially naked and were ornamented with earrings, feathers and golden pieces.

The Panche hunted and fought wars with their enemies using sticks and clubs and poisoned arrows. They used poison of spiders and snakes for their arrows.

Petroglyphs of the Panche were discovered in Tibacuy, Viotá, El Colegio, Cachipay, Albán, Sasaima. Rock paintings have been found in Tibacuy.

Like other indigenous peoples of the Americas, such as the Guane, the Panche performed cranial deformation.

According to Pedro Simón, the Panche performed cannibalism on parts of their conquered enemies. Some sources state they ate everything except for the heads, which they hung in their bohíos. However, later research by various researchers has found no evidence for cannibalism and attribute the cannibalistic ideas to the Spanish conquistadores.