Plethodidae is an extinct family of teleost fish that existed during the Late Cretaceous period. Fossils are known from North America, North Africa, and Europe.

Plethodids possessed thin, angelfish-like bodies and often had high dorsal fins which made them distinctive from other types of fish. Their skeletons were partially cartilaginous, though the amount varied from one species to another.

Plethodidae contains the following genera: