"Regina caeli" (Ecclesiastical Latin: [reˈdʒina ˈtʃeli]; Queen of Heaven) is a musical antiphon addressed to the Blessed Virgin Mary that is used in the liturgy of the Roman Rite of the Catholic Church during the Easter season, from Easter Sunday until Pentecost. During this season, it is the Marian antiphon that ends Compline (Night Prayer) and it takes the place of the traditional thrice-daily Angelus prayer.

In the past, the spelling Regina coeli was sometimes used, but this spelling is no longer found in official liturgical books.

The antiphon itself consists of four lines:

Regina caeli, laetare, alleluia;
Quia quem meruisti portare, alleluia,
Resurrexit, sicut dixit, alleluia:
Ora pro nobis Deum, alleluia.

Queen of heaven, rejoice, alleluia.
The Son you merited to bear, alleluia,
Has risen as he said, alleluia.
Pray to God for us, alleluia.

Compline, as revised in 1969 after the Second Vatican Council, ends with the antiphon alone. In the earlier Roman Breviary and in recitation at Angelus time during Eastertide, the following versicle and the following prayer are added to the antiphon:

A verse translation in 7.7.7.7 metre used in some Anglican churches is usually sung to the hymn tune known as the Easter Hymn "Christ the Lord is Risen Today" (Jesus Christ is risen today) or the hymn tune "Ave Virgo Virginum" (Hail Virgin of virgins):

The authorship of "Regina caeli" is unknown. It has been traced back to the 12th century and is found in an antiphonary of c. 1200 now in St Peter's Basilica in Rome. In the first half of the 13th century it was in Franciscan use, after compline.^{[citation needed]}