Reuben Garrett Lucius Goldberg was born on Independence Day in San Francisco, California, to Hannah and Max Goldberg. His father, a successful businessman, encouraged him to pursue a practical profession, setting the stage for Rube's initial foray into engineering.

Following his father's wishes, Goldberg earned a degree in engineering from the University of California, Berkeley. This provided him with a solid foundation in mechanics and problem-solving, skills which he later cleverly subverted and parodied in his cartoon creations.

After a brief stint working as an engineer for the city of San Francisco, Goldberg followed his passion and took a job as a sports cartoonist for the San Francisco Chronicle. This was his first formal entry into the world of art and laid the groundwork for his future success as a cartoonist.

Goldberg moved to New York City and began working for various newspapers, including the Evening Mail. It was here that he began to develop and popularize his signature style of cartooning featuring ridiculously complex inventions. His work quickly gained national recognition.

This period marked the rise in popularity of some of Goldberg's most iconic cartoon series, particularly those featuring Professor Lucifer G. Butts, the prototype for many of his future 'inventor' characters. These cartoons, depicting elaborate and impractical contraptions, cemented his fame and established the 'Rube Goldberg machine' as a cultural phenomenon.

Goldberg received the Pulitzer Prize for Editorial Cartooning for his cartoon "Peace Today," a commentary on the dangers of atomic warfare. This award recognized his ability to use his artistic skills to address serious social and political issues, demonstrating a broader range than just humorous inventions.

During World War II, Goldberg used his cartooning skills to support the war effort, creating propaganda posters and cartoons that encouraged patriotism and vigilance. His contributions helped boost morale and reinforce the importance of national unity.

In his later years, Goldberg transitioned into sculpture, creating abstract and whimsical pieces that reflected his inventive spirit. He continued to be a respected figure in the art world and remained active until his death.

Rube Goldberg passed away in New York City at the age of 87. His legacy lives on through his influential cartoons, the enduring concept of the 'Rube Goldberg machine', and numerous competitions and events that celebrate creativity, engineering, and humor.