Tafilah (Arabic: الطفيلة, romanized: 'aṭ-Ṭafīlah, [atˤ.tˤa.fiː.la]), also spelled Tafila, is a city with a population of 27,559 people in southwestern Jordan, located 183 kilometers (114 mi) southwest of Amman. It is the capital of Tafilah Governorate. It is well known for having green gardens which contain olive and fig trees, and grape-vines. Tafilah was first built by the Edomites and was called Tophel.

There are more than 360 natural springs in the Tafilah nahia, including the natural reservoir of Dana and hot natural springs at Afra and Burbeita. There are two phosphate and limestones mines in the Tafilah nahia, which are one of the country's main income sources.

The oldest state formation in Tafilah and South Jordan was the kingdom of Edom, and Tafilah lies on the ruins of the Edomite city of Tophel. The capital of Edom was Bozrah, now known as Busairah, 23 km to the south of Tafilah. Tafilah was later annexed by the Nabatean kingdom, which had its capital at Petra. Following the Roman invasion, it was ruled by the Ghassanids, under Byzantine authority. Tafilah then came under Muslim rule, interrupted for a brief period of time by Crusader rule. A certain Martin, who was a lord of Tafilah during the Crusader period, is mentioned in a text dated 1177. The remains beneath an Ottoman fort in Tafilah appear to belong to a Crusader castle.

In 1596 it appeared in the Ottoman tax registers under the name of Tafili, situated in the nahiya (subdistrict) of Karak, part of the Sanjak of Ajlun. It had 33 households who were Muslim. They paid a fixed tax-rate of 25% on agricultural products, including wheat (6300 a.), barley (3200 a.), olive trees/vineyards/fruit trees (2500 a.), a special product (bayt al–mal), goats and bee-hives (200 a.); in addition to occasional revenues (180 a.), and a market toll (120 a.). Their total tax was 12,500 akçe.

During the Arab Revolt, in January 1918, Tafilah and the region around it were captured in the Battle of Tafilah, thanks to what was described as a "brilliant feat of arms", by Arab troops under the command of T. E. Lawrence, Jaafar Pasha Al-Askari, and Prince Zeid bin Hussein.

In 1961, there were 4,506 inhabitants in Tafila. By 2015, the population had grown to 27,559, resulting in a growth rate of 512.5% from 1961 to 2015.

There is one university in Tafilah, Tafila Technical University. Founded in 1986 as a university college, it expanded to a university in 2005. The university as of the academic year 2009/2010 includes six colleges.

The city of Tafilah is organized into six districts: