Thomas Andrew Murphy (born December 30, 1945) is an American former Major League Baseball pitcher.

While pitching at Ohio University, the nineteen year old was originally drafted by the Houston Astros in the 18th round of the 1965 Major League Baseball draft, but did not sign. A year later, the San Francisco Giants drafted Murphy in the fourth round of the secondary phase of the draft, but he again did not sign. Finally, when the California Angels selected him sixth overall in the January 1967 draft, he signed.

Murphy hit the ground running in his first assignment in professional baseball with the Midwest League Quad Cities Angels. In six games, he went 5–1 with a 2.34 earned run average to earn a quick promotion to double A. In eight games with the El Paso Sun Kings, Murphy maintained a 2.76 ERA to earn a second promotion to the triple A Pacific Coast League's Seattle Angels, where he would finish out the 1967 season.

Following brief stints in El Paso and Seattle, Murphy was called up to the majors early in the 1968 season. After striking out seven in a no decision in his major league debut, Murphy earned a complete game victory over the New York Yankees in his second start. Murphy's own error in the third inning accounted for the Yankees' one unearned run. He was a hard luck loser on July 28 against the Chicago White Sox. After a rough first inning in which he gave up two runs, Murphy settled in to pitch seven innings of one hit ball. The Angels, however, were only able to plate one run off Jack Fisher. For the season, Murphy went 5–6 with a 2.17 ERA in fifteen starts.

Murphy was cursed with wildness in 1969. He led the American League with sixteen wild pitches and 21 hit batsmen on his way to a 10–16 record and 4.21 ERA. He rebounded with a career year in 1970. On May 7, he pitched his first career shutout over the Washington Senators. He went 16-13 for the season, the only season of his career in which he had a winning record. It was also his best season with the bat. He had a career bests .184 batting average and seven runs batted in. He also hit his only career home run off the Milwaukee Brewers' Lew Krausse Jr.

The wheels came off for Murphy in 1971. After winning his first start of the season, he dropped his next five decisions. He would also lose his final six decisions despite a relatively mild 3.31 ERA over that span. In Murphy's 36 starts, the Angels were shut out eight times, and scored just one run nine times, resulting in a 6–17 record.

In 1972, Murphy appeared in six games for the Angels, all in relief, when he was traded to the Kansas City Royals for Bob Oliver. He made three appearances out of the bullpen before he was moved into the starting rotation. He made his first start against his former franchise, and while he made a quality start (7 IP, 2 R), he came out on the losing end. He was 3–1 with a high 5.81 ERA when an injury kept him off the field for all of July and August. When he returned, he pitched his only shutout of the season before being shifted back to the bullpen for the remainder of the season. He earned his first career save against the Angels on September 19.

Despite the institution of the designated hitter in the American League in 1973, Murphy had two at bats on June 12, 1974, in an extra innings game between the Brewers and Royals. In the eleventh inning, he connected for a single to center off Marty Pattin.