WSB (750 kHz) is a commercial AM radio station in Atlanta, Georgia. It simulcasts a news/talk radio format with 95.5 WSBB-FM. WSB and WSBB-FM are the flagship stations for Cox Media Group which also owns three other Atlanta radio stations and WSB-TV. WSB is among the highest billing stations in the U.S. The station's studios and offices are in the WSB Television and Radio Group Building on West Peachtree Street in Midtown Atlanta.

WSB is powered at 50,000 watts, the maximum for commercial AM stations. WSB is a clear-channel class A station and uses a non-directional antenna. The station's transmitter and radiating tower are seven miles (11 kilometers) northeast of Atlanta at the Northlake Tower Festival Shopping Center, off Lavista Road in Tucker, Georgia. Its daytime coverage area is not as large as 50,000-watt AM stations in other parts of the country due to Georgia's poor ground conductivity; as such, a number of outer Atlanta suburbs only receive a grade B signal. At night, when radio waves travel farther, WSB can be heard with a good radio across much of the Southeastern United States, Gulf of Mexico and Caribbean Sea. Though the station is licensed for HD Radio operations, like many stations, it shut off the capability due to RF interference, a lack of demand for AM stations in the format, and the establishment of WSBB-FM to address audio quality concerns.

WSB was one of the first radio stations in the South. In early 1922, there was a tremendous public interest in the then-new technology of radio broadcasting. By the end of the year, the number of authorized stations exceeded 500. In many communities, a race broke out to see who would be the first to get a station on the air. In Atlanta, the primary contenders were the two major newspapers, the Atlanta Journal and the Atlanta Constitution. The Journal established a makeshift studio on the fifth floor of its building at 7 Forsyth Street. A transmitter had been ordered, but facing a delay, the newspaper arranged for the equipment used by Gordon Heidt for his amateur station to be temporarily installed. A broadcasting license was normally needed before a station could go on the air, but it was arranged to have an initial telegraphed authorization, which was sent by the Department of Commerce on the evening of March 15, 1922. The station's debut broadcast took place that evening. The transmitter had only 100 watts of power and ice was used to cool the batteries.

The Journal's new station was issued the randomly assigned call letters WSB. Station management would claim the call letters stood for "Welcome South, Brother", even though the Journal did not specifically request those call letters. The Constitution's station, WGM, debuted two days later on March 17. Because it also was transmitting on 360 meters, the two newspapers had to set up a time-sharing agreement allocating broadcast hours. Competition was so fierce between the two that WSB's manager, Lambdin "The Little Colonel" Kay, banned any person who had previously appeared on WGM from broadcasting over WSB.

In September 1922, the Department of Commerce set aside a second entertainment wavelength, 400 meters (750 kHz) for "Class B" stations that had quality equipment and programming. Both WSB and WGM were assigned to this new wavelength. In May 1923, additional "Class B" frequencies were made available, and Atlanta was assigned the use of 700 kHz. Once again, both WSB and WGM were assigned to this new frequency. However, at the end of July, WGM permanently ceased operations, which gave WSB exclusive use of the assignment.

In 1927, WSB became an affiliate of the NBC Red Network. The station carried NBC's dramas, comedies, news and sports during the "Golden Age of Radio". The trademark three-tone NBC chimes were first played in the WSB studios.

In the summer of 1927, WSB began transmitting on 630 kHz. On November 11, 1928, under the provisions of the Federal Radio Commission's General Order 40, WSB was reassigned to a "clear channel" frequency of 740 kHz. WSB was the dominant station nationally on this frequency. In March 1941, as part of the implementation of the North American Regional Broadcasting Agreement (NARBA), WSB moved to 750 kHz, where it has been heard ever since.

Part of WSB's programming was southern gospel music, gaining popularity throughout the region, with shows hosted by Charles Davis Tillman. The Shelby Star newspaper, in an issue dated November 1985, wrote that the talented Dan Hornsby, after the 1929 crash of the stock market, found himself working no longer for Columbia Records. He got work as the first morning show announcer for WSB. Lambdin Kay called Hornsby "90% of the local talent on WSB".