Electromagnetic interference (EMI), also called radio-frequency interference (RFI) when in the radio frequency spectrum, is a disturbance generated by an external source that affects an electrical circuit by electromagnetic induction, electrostatic coupling, or conduction. The disturbance may degrade the performance of the circuit or even stop it from functioning. In the case of a data path, these effects can range from an increase in error rate to a total loss of the data. Both human-made and natural sources generate changing electrical currents and voltages that can cause EMI: ignition systems, cellular network of mobile phones, lightning, solar flares, and auroras (northern/southern lights).^{[citation needed]} EMI frequently affects AM radios. It can also affect mobile phones, FM radios, and televisions, as well as observations for radio astronomy and atmospheric science.

EMI can be used intentionally for radio jamming, as in electronic warfare.

Since the earliest days of radio communications, the negative effects of interference from both intentional and unintentional transmissions have been felt and the need to manage the radio frequency spectrum became apparent.

In 1933, a meeting of the International Electrotechnical Commission (IEC) in Paris recommended the International Special Committee on Radio Interference (CISPR) be set up to deal with the emerging problem of EMI. CISPR subsequently produced technical publications covering measurement and test techniques and recommended emission and immunity limits. These have evolved over the decades and form the basis of much of the world's EMC regulations today.

In 1979, legal limits were imposed on electromagnetic emissions from all digital equipment by the FCC in the US in response to the increased number of digital systems that were interfering with wired and radio communications. Test methods and limits were based on CISPR publications, although similar limits were already enforced in parts of Europe.

In the mid 1980s, the European Union member states adopted a number of "new approach" directives with the intention of standardizing technical requirements for products so that they do not become a barrier to trade within the EC. One of these was the EMC Directive (89/336/EC) and it applies to all equipment placed on the market or taken into service. Its scope covers all apparatus "liable to cause electromagnetic disturbance or the performance of which is liable to be affected by such disturbance".

This was the first time there was a legal requirement on immunity, as well as emissions on apparatus intended for the general population. Although there may be additional costs involved for some products to give them a known level of immunity, it increases their perceived quality as they are able to co-exist with apparatus in the active EM environment of modern times and with fewer problems.

Many countries now have similar requirements for products to meet some level of electromagnetic compatibility (EMC) regulation.