Ziusudra (Old Babylonian Akkadian: 𒍣𒌓𒋤𒁺, romanized: Ṣíusudrá [ṣi₂-u₄-sud-ra₂], Neo-Assyrian Akkadian: 𒍣𒋤𒁕, romanized: Ṣísudda, Ancient Greek: Ξίσουθρος, romanized: Xísouthros) of Shuruppak is listed in the WB-62 Sumerian King List recension as the last king of Sumer prior to the Great Flood. He is subsequently recorded as the hero of the Eridu Genesis and appears in the writings of Berossus as Xisuthros.^{[citation needed]}

Ziusudra is one of several mythic characters who are protagonists of Near Eastern flood myths, including Atrahasis, Utnapishtim, and the biblical Noah. Although each story displays its own distinctive features, many key story elements are common to two, three, or all four versions.^{[citation needed]}

In the WB-62 Sumerian king list recension, Ziusudra, or Zin-Suddu of Shuruppak, is listed as son of the last king of Sumer before a great flood. He is recorded as having reigned as both king and gudug priest for ten sars (periods of 3,600 years), although this figure is probably a copyist error for ten years. In this version, Ziusudra inherited rulership from his father Ubara-Tutu, who ruled for ten sars.

The lines following the mention of Ziusudra read:

Then the flood swept over. After the flood had swept over, and the kingship had descended from heaven, the kingship was in Kish.

The city of Kish flourished in the Early Dynastic period soon after a river flood archaeologically attested by sedimentary strata at Shuruppak (modern Tell Fara), Uruk, Kish, and other sites, all of which have been radiocarbon dated to ca. 2900 BC. Polychrome pottery from the Jemdet Nasr period (ca. 30th century BC), which immediately preceded the Early Dynastic I period, was discovered directly below the Shuruppak flood stratum. Max Mallowan wrote that "we know from the Weld Blundell prism [i.e. WB-62] that at the time of the Flood, Ziusudra, the Sumerian Noah, was King of the city of Shuruppak where he received warning of the impending disaster. His role as a saviour agrees with that assigned to his counterpart Utnapishtim in the Gilgamesh Epic. ... both epigraphical and archaeological discovery give good grounds for believing that Ziusudra was a prehistoric ruler of a well-known historic city the site of which has been identified."

That Ziusudra was a king from Shuruppak is supported by the Gilgamesh XI tablet, which makes reference to Utnapishtim (the Akkadian translation of the Sumerian name Ziusudra) with the epithet "man of Shuruppak" at line 23.

The tale of Ziusudra is known from a single fragmentary tablet written in Sumerian, datable by its script to the 17th century BC (Old Babylonian Empire), and published in 1914 by Arno Poebel. The first part deals with the creation of man and the animals and the founding of the first cities Eridu, Bad-tibira, Larak, Sippar, and Shuruppak. After a missing section in the tablet, we learn that the gods have decided to send a flood to destroy mankind. The god Enki (lord of the underworld sea of fresh water and Sumerian equivalent of Babylonian god Ea) warns Ziusudra, the ruler of Shuruppak, to build a large boat; the passage describing the directions for the boat is also lost. When the tablet resumes, it is describing the flood. A terrible storm raged for seven days, "the huge boat had been tossed about on the great waters," then Utu (Sun) appears and Ziusudra opens a window, prostrates himself, and sacrifices an ox and a sheep. After another break, the text resumes, the flood is apparently over, and Ziusudra is prostrating himself before An (Sky) and Enlil (Lordbreath), who give him "breath eternal" and take him to dwell in Dilmun. The remainder of the poem is lost.^{[failed verification]}