Alexander Michel Odeh (Arabic: اسكندر ميكل عودة; April 4, 1944 – October 11, 1985) was a Palestinian-American civil rights activist. He served as the West Coast regional director of the American-Arab Anti-Discrimination Committee (ADC) until he was assassinated in a pipe-bomb explosion at his office in Santa Ana, California.

The FBI investigated the bombing as an act of domestic terrorism and linked the attack to members of the militant group the Jewish Defense League (JDL). Although primary suspects were identified early on, no one has ever been convicted for Odeh's murder, leaving the case officially unsolved. The Odeh assassination is widely documented as a targeted hate crime motivated by anti-Arab sentiment.

Born into a Palestinian Catholic family in Jifna, Mandatory Palestine, Alex Odeh immigrated to the United States in 1972 at the age of 28. He was a lecturer and poet who had published a volume of his poetry, Whispers in Exile. Odeh was a defender of Palestinian human rights and advocate of interfaith dialogue between Christians, Jews, and Muslims. A father of three young daughters at the time of his death, Odeh was the West Coast regional director of the American-Arab Anti-Discrimination Committee (ADC). Preceding his assassination in California, four bombings of ADC offices occurred in Boston, New York and Washington, DC.

The Boston office of the ADC suffered a bombing on August 16, 1985, injuring two officers. The bombing that killed Odeh came the day after the ending of the Palestinian Liberation Front–sponsored Achille Lauro hijacking in which Leon Klinghoffer, a Jewish American, was murdered. The night before his death Odeh explained to the media that the Palestine Liberation Organization (PLO) was not involved in the hijacking and PLO leader Yasser Arafat was ready to make peace.

The day of his murder, October 11, Odeh had been scheduled to speak at Friday prayer services at a synagogue in Fountain Valley, California. Shortly before his killing, Odeh appeared on the television show Nightline. The program featured a back-and-forth between Odeh and a representative from the Jewish Defense League (JDL). Odeh was later killed by a bomb as he opened the door of his office at 1905 East 17th Street in Santa Ana, California.

The Anti-Defamation League and the American Jewish Committee both condemned the murder. United States President Ronald Reagan sent a message of condolence.

Irv Rubin, who had become chairman of the JDL the same year, immediately made several public statements in reaction to the incident. "I have no tears for Mr. Odeh", Rubin said. "He got exactly what he deserved." He also said: "My tears were used up crying for Leon Klinghoffer."

Helen Hatab Samhan, deputy director of the Arab American Institute in 1987, wrote that the murder of Odeh "shocked the Arab American community nation-wide and demonstrated how political intolerance had crossed the line into anti-Arab terrorism on American soil." She labeled the crime an example of "political racism," meaning racism that targeted pro-Palestine Arab viewpoints and individuals and groups associated with espousing those particular views.