Following his doctorate, Skinner held positions as a National Research Council Fellow and then a Junior Fellow at Harvard. This period allowed him to dedicate himself fully to research, refine his experimental methods, and develop his concepts of operant conditioning.

Skinner accepts a position as an instructor at the University of Minnesota. He continues his research and begins to teach courses on psychology.

Skinner moves to Indiana University, where he advances from assistant professor to associate professor. He establishes a laboratory for behavioral research and continues to refine his operant conditioning techniques.

Skinner briefly serves as the chair of the psychology department at Indiana University before returning to Harvard University.

Skinner returns to Harvard University as a Professor of Psychology, a position he holds for the majority of his career. He becomes a prominent figure in the field, influencing generations of students and researchers. He develops and disseminates his theories of operant conditioning and radical behaviorism.

Even after becoming Professor Emeritus, Skinner remained active in research, writing, and lecturing. He continued to defend and promote behaviorism until his death. He published several influential books and articles during this period.